Linatab E 25 mg+5 mg (Tablet)

Unit Price: ৳ 40.00 (3 x 10: ৳ 1,200.00)
Strip Price: ৳ 400.00

Medicine Details

Indications

  • Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus

Pharmacology

  • Linagliptin inhibits DPP-4 enzyme
  • Empagliflozin inhibits Sodium-glucose co-transporter 2 (SGLT2)

Dosage & Administration

  • Recommended dose: 10 mg Empagliflozin and 5 mg Linagliptin once daily, taken in the morning, with or without food
  • Increased dose: Dose may be increased to 25 mg Empagliflozin and 5 mg Linagliptin once daily
  • Renal impaired patients: Assess renal function before initiating this tablet

Interaction

  • Coadministration with diuretics
  • Coadministration with Insulin or Insulin Secretagogues
  • Coadministration with inducers of P-glycoprotein or CYP3A4 Enzymes
  • Positive Urine Glucose Test
  • Interference with 1,5-anhydroglucitol (1,5-AG) Assay

Contraindications

  • Severe renal impairment, end-stage renal disease, or dialysis
  • History of hypersensitivity reaction to Linagliptin or Empagliflozin

Side Effects

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues
  • Necrotizing Fasciitis of the Perineum (Fournier’s Gangrene)
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Severe and Disabling Arthralgia
  • Bullous Pemphigoid
  • Heart Failure

Pregnancy & Lactation

  • Not recommended during the second and third trimesters of pregnancy

Precautions & Warnings

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia
  • Genital Mycotic Infections
  • Hypersensitivity
  • Heart Failure

Overdose Effects

  • Contact Poison Control Center
  • Employ usual supportive measures

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Store below 30°C temperature
  • Keep away from light and wet place
  • Keep out of reach of children

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