Linatab E 25 mg+5 mg (Tablet)
Unit Price: ৳ 40.00 (3 x 10: ৳ 1,200.00)
Strip Price: ৳ 400.00
Medicine Details
Category | Details |
---|---|
Generic | Empagliflozin linagliptin |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus
Pharmacology
- Linagliptin inhibits DPP-4 enzyme
- Empagliflozin inhibits Sodium-glucose co-transporter 2 (SGLT2)
Dosage & Administration
- Recommended dose: 10 mg Empagliflozin and 5 mg Linagliptin once daily, taken in the morning, with or without food
- Increased dose: Dose may be increased to 25 mg Empagliflozin and 5 mg Linagliptin once daily
- Renal impaired patients: Assess renal function before initiating this tablet
Interaction
- Coadministration with diuretics
- Coadministration with Insulin or Insulin Secretagogues
- Coadministration with inducers of P-glycoprotein or CYP3A4 Enzymes
- Positive Urine Glucose Test
- Interference with 1,5-anhydroglucitol (1,5-AG) Assay
Contraindications
- Severe renal impairment, end-stage renal disease, or dialysis
- History of hypersensitivity reaction to Linagliptin or Empagliflozin
Side Effects
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Urosepsis and Pyelonephritis
- Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues
- Necrotizing Fasciitis of the Perineum (Fournier’s Gangrene)
- Genital Mycotic Infections
- Hypersensitivity Reactions
- Severe and Disabling Arthralgia
- Bullous Pemphigoid
- Heart Failure
Pregnancy & Lactation
- Not recommended during the second and third trimesters of pregnancy
Precautions & Warnings
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Urosepsis and Pyelonephritis
- Hypoglycemia
- Genital Mycotic Infections
- Hypersensitivity
- Heart Failure
Overdose Effects
- Contact Poison Control Center
- Employ usual supportive measures
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store below 30°C temperature
- Keep away from light and wet place
- Keep out of reach of children