Ezitor 10 mg+10 mg (Tablet)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Atorvastatin ezetimibe
Company Navana pharmaceuticals ltd
Also available as
Ezitor 20 mg tablet

Indications

  • Reduction of elevated total cholesterol
  • Reduction of low density lipoprotein cholesterol
  • Increase of high-density lipoprotein cholesterol
  • Treatment of primary hyperlipidemia
  • Treatment of homozygous familial hypercholesterolemia
  • Adjunct to diet and nonpharmacologic measures

Pharmacology

  • Inhibition of HMG-CoA reductase
  • Cholesterol synthesis inhibition in the liver
  • Increase in hepatic LDL receptors
  • Reduction of LDL production
  • Inhibition of absorption of cholesterol
  • Localization at the brush border of the small intestine

Dosage & Administration

  • Dosage range of 10/10 mg to 80/20 mg daily
  • Recommended starting dose of 10/10 mg or 20/10 mg daily
  • Single dose administration
  • Analysis of lipid levels within 2 or more weeks
  • Dosage adjustment according to lipid levels
  • Dosage in patients with hepatic impairment

Interaction

  • Increased risk of myopathy with fibric acid derivatives
  • Enhanced risk of myopathy when combined with niacin
  • Monitoring required when coadministered with digoxin
  • Consideration of AUC values when coadministered with oral contraceptives

Contraindications

  • Active liver disease
  • Hypersensitivity to components of the preparation

Side Effects

  • Rhabdomyolysis
  • Myopathy
  • Liver enzyme abnormalities
  • Abdominal pain

Pregnancy & Lactation

  • Pregnancy Category X
  • Contraindicated in pregnant women
  • No benefit during pregnancy
  • Unknown excretion in human milk

Precautions & Warnings

  • Cases of myopathy and rhabdomyolysis reported
  • Temporary withholding in acute, serious conditions
  • Liver enzyme tests recommended prior to therapy initiation
  • Caution when coadministered with drugs affecting endogenous steroid hormones

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients

Overdose Effects

  • Symptomatic treatment
  • Supportive measures as required

Therapeutic Class

  • Other lipid regulating drugs

Storage Conditions

  • Do not store above 30°C
  • Keep in a dry place
  • Protect from light
  • Keep out of reach of children

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