Serofit 50 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Category Details
Generic Sertraline hydrochloride
Company Everest pharmaceuticals ltd
Also available as
Serofit 25 mg tablet

Indications

  • Major depressive disorder (MDD)
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder (PD)
  • Post-traumatic stress disorder (PTSD)
  • Social anxiety disorder (SAD)
  • Premenstrual dysphoric disorder (PMDD)

Pharmacology

Sertraline has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites. Its prolonged elimination half-life offers a benefit of once daily administration.

Dosage & Administration

  • Adults:
    • Major depressive disorder:
      • Starting Dose: 50 mg
      • Therapeutic Range: 50-200 mg
    • Obsessive-compulsive disorder:
      • Starting Dose: 50 mg
      • Therapeutic Range: 50-200 mg
    • Panic disorder, Post-traumatic stress disorder, Social anxiety disorder:
      • Starting Dose: 25 mg
      • Therapeutic Range: 50-200 mg
    • Pediatric Patients (ages 6-12 years old):
      • Obsessive-compulsive disorder:
        • Starting Dose: 25 mg
        • Therapeutic Range: 50-200 mg
    • Premenstrual dysphoric disorder (PMDD): Starting dosage for PMDD is 50 mg/day. Intermittent dosing would be repeated with each new cycle.

Interaction

Serofit may interact with drugs that are highly bound to plasma proteins, like Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol, etc.

Contraindications

Sertraline is contraindicated in patients with a known hypersensitivity to Sertraline or any of the excipients of the drug. It is not recommended in patients with moderate to severe hepatic impairment.

Side Effects

  • Upset stomach
  • Diarrhoea
  • Constipation
  • Vomiting
  • Dry mouth
  • Loss of appetite
  • Weight changes
  • Drowsiness
  • Dizziness
  • Headache
  • Pain
  • Burning or tingling in the hands or feet
  • Sore throat

Pregnancy & Lactation

Sertraline's safety during human pregnancy has not been established. It is excreted in breast milk. If treatment with Sertraline is considered necessary, discontinuation of breast-feeding should be considered.

Precautions & Warnings

Precaution should be taken in case of liver problems, kidney diseases, seizures, heart problems, and any allergies. Caution is advised while using Serofit in the elderly. Risk of suicidal thinking and change of behavior may occur.

Therapeutic Class

SSRIs & related anti-depressant drugs

Storage Conditions

Do not store above 30°C. Keep out of the reach of children.

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