Renesis 50 mg (Tablet)
Unit Price: ৳ 350.00 (2 x 3: ৳ 2,100.00)
Strip Price: ৳ 1,050.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Roxadustat |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Treatment of symptomatic anemia associated with chronic kidney disease (CKD)
Description
- First-in-class HIF-PH inhibitor
- Orally administered
- Promotes erythropoiesis
- Improves iron regulation
Pharmacology
- Orally bioavailable
- Inhibits HIF-PH
- Increases endogenous erythropoietin production
- Reduces hepcidin expression
Dosage & Administration
- Oral administration
- Dosage individualized for target Hb levels
- Dose adjustment guidelines provided
- Tablets taken three times per week
- Should not be taken on consecutive days
Interaction
- Potential drug-drug interactions with phosphate binders, gemfibrozil, and probenecid
Side Effects
- Common adverse reactions include hypertension, thrombosis, diarrhea, peripheral edema, hyperkalemia, and nausea
Pregnancy & Lactation
- Contraindicated during pregnancy and breastfeeding
Precautions & Warnings
- Caution in patients with pre-existing risk factors for thrombotic vascular events, history of seizures, signs of infection, or liver disorder
Use in Special Populations
- Not indicated for use in children or patients with severe hepatic impairment
Overdose Effects
- May cause increased heart rate
- Appropriate measures for dose reduction or interruption required
Therapeutic Class
- Drugs for Haemolytic Hypoplastic & Renal Anemia
Storage Conditions
- Store below 30°C, in a dry place, away from light and moisture