Cozid 250 mg/vial (IM/IV Injection)

250 mg vial: ৳ 85.00

Medicine Details

Indications

  • Lower Respiratory Tract Infections
  • Skin and Skin Structure Infections
  • Urinary Tract Infections
  • Bacterial Septicemia
  • Bone and Joint Infections
  • Gynecologic Infections
  • Intraabdominal Infections
  • Central Nervous System Infections

Pharmacology

  • Bactericidal action
  • Inhibition of enzymes responsible for cell-wall synthesis
  • Susceptibility to gram-negative organisms
  • Activity against gram-positive organisms
  • Stability to beta-lactamases

Dosage

  • Usual adult dosage of 1 gram every 8 to 12 hours
  • Dosage determined by susceptibility of causative organisms
  • Adult dosage range of 1 to 6 gm per day
  • Different dosages for urinary tract infections and severe infections
  • Reduced clearance in acutely ill elderly patients

Administration

  • Intravenous or deep IM injection
  • Reconstitution with Sterile Water for Injection
  • Avoidance of intra-arterial administration

Contraindications

  • Hypersensitivity to Ceftazidime or cephalosporin antibiotics

Side Effects

  • Local reactions following IV injection
  • Allergic and gastrointestinal reactions
  • Hypersensitivity reactions
  • Gastrointestinal symptoms
  • Central nervous system reactions

Pregnancy & Lactation

  • Use in pregnancy only if clearly needed
  • Excretion in human milk at low concentrations
  • Consideration of discontinue nursing or drug

Precautions & Warnings

  • Reduction in total daily dosage for patients with renal insufficiency
  • Caution in individuals with history of gastrointestinal disease

Use in Special Populations

  • Dosage reduction for impaired renal function
  • Usage in peritoneal dialysis and CAPD
  • No dosage adjustment for impaired hepatic function

Overdose Effects

  • Seizure activity
  • Encephalopathy
  • Neuromuscular excitability
  • Coma
  • Supportive treatment for acute overdosage

Therapeutic Class

  • Third generation Cephalosporins

Reconstitution

  • Amount of WFI for various dosages and routes of administration

Storage Conditions

  • Storage below 25°C
  • Protection from light and moisture
  • Stability of reconstituted solutions for up to 24 hours at 2°C-8°C

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