Eurix 125 mg/5 ml (Powder for Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefuroxime axetil |
| Company | Ethical drugs limited |
| Also available as |
Indications
- Treatment of infections caused by sensitive bacteria
- Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
- Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
- Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
- Lower respiratory tract infections including pneumoniae, caused by various pathogens
- Skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
- Urinary tract infections caused by E.coli or Klebsiella pneumoniae
- Bone and Joint Infections caused by Staphylococcus aureus
- Gonorrhoea caused by Neisseria gonorrhoeae
- Early Lyme Disease caused by Borrelia burgdorferi
Pharmacology
Well-characterized and effective antibacterial agent with broad-spectrum bactericidal activity against a wide range of common pathogens, including β-lactamase producing strains.
Dosage
- Various dosages for different age groups and types of infections, both oral and parenteral administration
Mode of Action
Good stability to bacterial β-lactamase and consequently, is active against many ampicillin-resistant and amoxycillin-resistant strains.
Administration
Use of freshly reconstituted solution is recommended. Potency maintained for at least 24 hours at room temperature or 48 hours at 5<sup>o</sup> C.
Interaction
No potentially hazardous interactions reported.
Contraindications
Contraindicated in patients with known allergy to Cephalosporins.
Side Effects
Infrequent and generally mild adverse effects including rashes and gastrointestinal disturbances. Prolonged use may result in the overgrowth of non susceptible organisms like Candida.
Pregnancy & Lactation
US FDA pregnancy category B. Cefuroxime have been shown to be excreted in human milk. Caution should be exercised when administered to a nursing woman.
Precautions & Warnings
Should be given with care to patients receiving concurrent treatment with potent diuretics & who has history of colitis. Cross reactions with penicillin have been reported.
Therapeutic Class
Second generation Cephalosporins
Reconstitution
Instructions for reconstitution for different intramuscular and intravenous injections.
Storage Conditions
Store in a cool, dry place (below 30<sup>o</sup> C), away from light & moisture. Keep out of the reach of children.