Nilicon 1 gm/vial (IM Injection)
1 gm vial: ৳ 180.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Ethical drugs limited |
| Also available as |
Indications
- Treatment of lower respiratory tract infections
- Treatment of acute bacterial otitis media
- Treatment of skin and skin structure infections
- Treatment of urinary tract infections
- Treatment of gonorrhea
- Treatment of bacterial septicemia
- Treatment of bone and joint infections
- Treatment of meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
- Broad-spectrum parenteral cephalosporin antibiotic
- Potent bactericidal activity
- Interferes with synthesis of bacterial cell wall
- High stability in the presence of beta lactamases
- Long plasma elimination half-life (6 to 9 hours)
- Not metabolized in the body
- Excreted unchanged in the urine (40-65%)
- Highly protein bound (95%)
Dosage
- Usual adult dose: 1 to 2 gm by intravenous or intramuscular administration once a day
- Maximum adult dose: 4 gm/day
- Usual pediatric dose: 50 to 75 mg/kg intravenous or intramuscular administration once a day
- Maximum pediatric dose: 2 gm/day
- Duration of therapy: 4 to 14 days
- Infants and children (01 month or older) dosage
Administration
- Preparation of solutions for intramuscular / intravenous injections
- Injection administration over 2-4 minutes
- Patient tolerance test before starting treatment
- Solution potency maintenance at room temperature and 5°C
Interaction
- No reported drug interactions
Contraindications
- Hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects
- Cutaneous reactions
- Hematologic reactions
- Hepatic reactions
- CNS reactions
- Local phlebitis
Pregnancy & Lactation
- Safety in human pregnancy not established
- Caution in lactating mothers
Precautions & Warnings
- Risk of anaphylactic shock
- Detection of gallbladder shadows
- Blood picture checks during prolonged treatment
Use in Special Populations
- Avoid use in premature and newborn neonates
Overdose Effects
- No specific antidote, symptomatic treatment
Therapeutic Class
- Third generation cephalosporins
Storage Conditions
- Store in a cool, dry place (below 30°C)