Olmepin 5 mg+40 mg (Tablet)
Unit Price: ৳ 16.00 (3 x 10: ৳ 480.00)
Strip Price: ৳ 160.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate olmesartan medoxomil |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of hypertension alone or with other antihypertensive agents
- Lowering blood pressure
- Initial therapy for patients likely to need multiple antihypertensive agents
- Individualized treatment based on baseline blood pressure and patient risk
Pharmacology
- Amlodipine - dihydropyridine calcium channel blocker
- Greater effect on vascular smooth muscle cells than on cardiac muscle cells
- Peripheral arterial vasodilator
- Olmesartan Medoxomil - blocks vasoconstrictor and aldosterone-secreting effects of angiotensin II
Dosage & Administration
- Substitute individually titrated components for patients
- Initial therapy with 5/20 mg once daily
- Titration up to a maximum of 10/40 mg once daily
- Recommended starting dose of Amlodipine is 2.5 mg in patients 75 years
Interaction
- Attenuation of antihypertensive effect by NSAIDs and selective COX-2 inhibitors
- Close monitoring of blood pressure, renal function, and electrolytes
Contraindications
- Cannot be co-administered with Aliskiren in patients with diabetes
Side Effects
- Peripheral edema
- Headache
- Flushing
- Dizziness
- Sprue-like enteropathy
Pregnancy & Lactation
- Pregnancy Category D
- Avoid use in 2nd and 3rd trimester
- Potential fetal death
- Consideration for discontinuation during nursing
Precautions & Warnings
- Caution in volume- or salt-depleted patients
- Vasodilation in patients with severe aortic stenosis
- Increased risk for angina or acute MI in patients with severe obstructive coronary artery disease
Use in Special Populations
- Pediatric use not established
- No overall differences in safety or effectiveness observed in geriatric use
- No studies in patients with renal impairment
- Initial therapy not recommended in hepatically impaired patients
Overdose Effects
- No information on overdose in humans
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Keep away from light
- Keep out of the reach of children