Cardogrel Plus 75 mg+75 mg (Tablet)

Unit Price: ৳ 11.04 (3 x 10: ৳ 331.20)

Strip Price: ৳ 110.40

Medicine Details

Category	Details
Generic	Clopidogrel aspirin
Company	Pharmasia limited

Title

Cardogrel Plus

Description

Anti-platelet drug indicated for reducing the rate of Myocardial Infarction (MI) and Stroke in patients with acute coronary syndrome (ACS), recent MI, recent Stroke, or established Peripheral Arterial Disease.

Color Options

White
Blue

Formulation

Oral tablets

Brand

Cardogrel Plus

Dosage Strength

75 mg

Packaging Type

Blister pack

Active Ingredients

Clopidogrel
Aspirin

Pharmacological Action

Inhibition of platelet activation and aggregation

Pharmacokinetics

Absorption: Rapid absorption after oral administration
Metabolism: Extensively metabolized by the liver
Elimination: Approximately 50% excreted in the urine

Recommended Dosage

75 mg once daily

Loading Dose for ACS

300 mg once

Additional Medication

Recommended to be taken in combination with Aspirin (75 mg-325 mg once daily)

Drug Interactions

Aspirin: Potentiates the effect of aspirin on collagen-induced platelet aggregation
Heparin: Does not alter the effect of heparin on coagulation
NSAIDs: Associated with increased occult gastrointestinal blood loss
Warfarin: Safety not established, should be used with caution

Contraindications

Hypersensitivity to the drug substance
Active pathological bleeding

Side Effects

Generally well tolerated

Pregnancy & Lactation

Pregnancy: Should be used during first and second trimesters if clearly needed
Lactation: Unknown excretion in human breast milk, contraindicated during breastfeeding

Precautions & Warnings

May prolong bleeding time
Risk of Thrombotic thrombocytopenic purpura (TTP)
Risk of Reye's syndrome in individuals with chicken pox, influenza or flu symptoms

Use in Special Populations

Children: Should not be given to children under 12 years unless benefits outweigh risks

Overdose Effects

Clopidogrel: May lead to bleeding complications, platelet transfusion may restore clotting ability
Aspirin: May cause dizziness, headache, tinnitus, confusion, and gastrointestinal symptoms