Steclo 0.05% (Ointment)
10 gm tube: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clobetasol propionate |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- Psoriasis (excluding widespread plaque psoriasis)
- Recalcitrant dermatoses
- Lichen planus
- Discoid lupus erythematosus
- Other skin conditions which do not respond satisfactorily to less potent steroids
Composition
- Clobetasol Propionate Cream: Each gram cream contains Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Ointment: Each gram ointment contains Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Scalp Application: Each gram lotion contains Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Shampoo: Each gram shampoo contains Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Lotion: Each gram lotion contains Clobetasol Propionate BP 0.5 mg (0.05% w/w)
- Clobetasol Propionate Spray: Each gram spray contains Clobetasol Propionate BP 0.5 mg (0.05% w/w)
Pharmacology
- Very potent topical corticosteroid
- Anti-inflammatory, antipruritic and vasoconstrictive properties
- Inhibits late phase allergic reactions
- Decreases mast cell density
- Reduces cytokine production
Dosage
- Apply a thin layer of Clobetasol Propionate Cream or Ointment twice daily
- Limited to 2 consecutive weeks maximum
- Apply required quantity of spray of once or twice daily for Scalp Application
Administration
- Route of administration: Cutaneous
- Creams suitable for moist or weeping surfaces
- Ointments suitable for dry, lichenified or scaly lesions
Interaction
- Co-administered drugs inhibiting CYP3A4 can increase systemic exposure
Contraindications
- Rosacea, acne vulgaris and perioral dermatitis
- Hypersensitivity to the preparation
- Not for use in children under one year of age
Side Effects
- Hypercorticism from systemic absorption
- Local atrophic changes in the skin
- Pigmentation changes and hypertrichosis
Pregnancy & Lactation
- Limited data on use during pregnancy
- Caution advised during lactation
Precautions & Warnings
- Avoid long-term continuous therapy, especially in infants and children
- Atrophic changes possible on the face after prolonged treatment
- Clinical supervision important in psoriasis treatment
Use in Special Populations
- Avoid long-term therapy in infants and children under 12 years
Overdose Effects
- Acute overdosage unlikely
- Features of hypercortisolism with chronic over-dosage
Therapeutic Class
- Other Topical corticosteroids
Storage Conditions
- Keep below 30°C temperature
- Protected from light and moisture
- Do not freeze