Clas 75 mg+75 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Clopidogrel aspirin
Company Delta pharma ltd

Title and Categories

  • Clopidogrel Tablets
  • Medicine
  • Pharmacology
  • Therapeutic Class
  • Anti-platelet drugs

Indications

  • Reduces the rate of Myocardial Infarction (MI)
  • Reduces the rate of Stroke
  • Treatment for Acute Coronary Syndrome (ACS)
  • Treatment for recent MI or Stroke
  • Treatment for Peripheral Arterial Disease

Pharmacology

  • Inhibits platelet activation and aggregation
  • Irreversible binding to P2Y12 class of ADP receptors on platelets
  • Dose-dependent inhibition of platelet aggregation
  • Metabolized by the liver
  • Rapid absorption after oral administration

Dosage and Administration

  • Recommended dose of 75 mg once daily
  • Can be taken with or without food
  • Initiation with a single 300 mg loading dose for acute coronary syndrome
  • Combination with Aspirin (75 mg-325 mg once daily)
  • Elderly and renal patients do not require dosage adjustment

Interaction

  • No modification of Clopidogrel-mediated inhibition by Aspirin
  • Potentiates the effect of aspirin on collagen-induced platelet aggregation
  • Does not alter the effect of heparin on coagulation
  • Increased occult gastrointestinal blood loss when co-administered with NSAIDs

Contraindications

  • Hypersensitivity to the drug substance
  • Active pathological bleeding such as peptic ulcer or intracranial hemorrhage

Side Effects

  • Generally well tolerated

Pregnancy and Lactation

  • Use during first and second trimesters if clearly needed
  • Contraindicated during the third trimester
  • Unknown excretion in human breast milk

Precautions and Warnings

  • May prolong bleeding time
  • Rare reports of Thrombotic thrombocytopenic purpura (TTP)
  • Possible development of Reye's syndrome in individuals with specific conditions
  • Reported hypersensitivity reactions

Use in Special Populations

  • Not recommended for children under 12 years
  • Aspirin may contribute to Reye’s syndrome in some children

Overdose Effects

  • May lead to bleeding complications
  • Moderate and severe Aspirin intoxication symptoms and treatment

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

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