Glemep 4 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Glimepiride
Company Healthcare pharmaceuticals ltd
Also available as
Glemep 2 mg tablet Glemep 1 mg tablet

Indications

  • Adjunct to diet and exercise for Type II diabetes mellitus
  • Use in combination with metformin
  • Use in combination with insulin
  • Increased risk of hypoglycemia with combined use of Glemep and insulin

Pharmacology

  • Decreases blood glucose concentration
  • Stimulates release of insulin
  • Improves sensitivity of beta cells to glucose stimulus
  • Reduction of basal hepatic glucose production

Dosage

  • Initial dose: 1 mg once daily
  • Dosage titration based on regular blood sugar monitoring
  • Timing and distribution of doses decided by physician
  • Consideration for dose adjustment with changes in weight or lifestyle

Administration

  • Tablet must be swallowed with sufficient liquid

Interaction

  • Potentiating interactions with ACE inhibitors, chloramphenicol, fluoxetine, sulphonamides, etc.
  • Attenuating interactions with barbiturates, calcium channel blockers, corticosteroids, etc.
  • Potential masking of hypoglycemic symptoms with certain drug interactions

Contraindications

  • Not suitable for type I diabetes mellitus
  • Avoid in diabetic ketoacidosis
  • Avoid in patients hypersensitive to sulfonylureas
  • Avoid in severe hepatic dysfunction and renal impairment

Side Effects

  • Hypoglycemia
  • Temporary visual impairment
  • Nausea, vomiting, diarrhea
  • Abdominal pain, urticaria, fall in blood pressure

Pregnancy & Lactation

  • Avoid during pregnancy, consider changeover to insulin
  • Avoid while breastfeeding, consider discontinuation of breastfeeding

Precautions & Warnings

  • Increased risk of hypoglycemia in initial weeks of treatment
  • Careful monitoring required with dosage adjustments
  • Prompt control of hypoglycemia with carbohydrate intake

Overdose Effects

  • Hypoglycemia risk with overdosage
  • Treatment with oral glucose
  • Severe cases may require hospitalization and IV glucose administration

Therapeutic Class

  • Sulfonylureas

Storage Conditions

  • Store below 30°C
  • Keep away from light
  • Keep out of reach of children

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