Quinoflox 200 mg (Tablet)
Unit Price: ৳ 15.00 (1 x 10: ৳ 150.00)
Strip Price: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Sparfloxacin |
| Company | Healthcare pharmaceuticals ltd |
Indications
- Community-acquired pneumonia
- Chronic Obstructive Pulmonary Disease
- Acute Maxillary Sinusitis
- Urinary tract infections
- Bacterial prostatitis
- Bacterial diarrhea
- Osteomyelitis
- Tuberculosis treatment
- Leprosy treatment
Pharmacology
- Broad-spectrum antibacterial agent
- Inhibition of DNA gyrase
- Inhibition of topoisomerase IV
- Effectiveness against gram positive organisms
- High plasma protein binding
- Liver metabolism
- Excretion in feces and urine
Dosage & Administration
- Recommended daily dose for normal renal function
- Recommended daily dose for renal impairment
Interaction
- Chelation complexes with antacids and sucralfate
- Potential interaction with medications affecting QTc interval
Contraindications
- Hypersensitivity to ingredients
- Pregnancy and lactation
- Glucose-6-Phosphate Dehydrogenase deficiency
- History of Achilles tendinitis following fluoroquinolones use
Side Effects
- Photosensitivity reaction
- Diarrhea
- Nausea
- Headache
- Dyspepsia
- Dizziness
- Insomnia
- Abdominal pain
- Pruritus
- Taste perversion
- QTc interval prolongation
- Vomiting
- Flatulence
- Vasodilatation
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
Precautions & Warnings
- Moderate to severe phototoxic reactions
- Discontinuation advice for phototoxicity reaction
- Lack of established safety and effectiveness in children, adolescents, pregnant women, and lactating women
- Adequate hydration maintenance
- Caution in renal insufficiency
- Avoidance of concomitant prescription with QTc prolonging medications
- Sunlight exposure avoidance
Use in Special Populations
- Unaltered pharmacokinetics in the elderly with normal renal function
- Lack of studied pharmacokinetics in pediatric subjects
- No gender differences in pharmacokinetics
- Lengthened terminal elimination half-life in renal impairment
- Unaltered pharmacokinetics in mild or moderate hepatic impairment without cholestasis
Therapeutic Class
- 4-Quinolone preparations
Storage Conditions
- Keep out of reach of children
- Store away from heat and direct light
- Store below 30°C