Clognil Plus 75 mg+75 mg (Tablet)

Unit Price: ৳ 12.04 (3 x 10: ৳ 361.20)

Strip Price: ৳ 120.40

Medicine Details

Category	Details
Generic	Clopidogrel aspirin
Company	Orion pharma ltd

Indications

Reduction of Myocardial Infarction (MI)
Reduction of Stroke
Unstable Angina (UA)
Non-ST-elevation Myocardial Infarction (NSTEMI)
ST-elevation Myocardial Infarction (STEMI)
Peripheral Arterial Disease

Pharmacology

Clopidogrel as prodrug
Inhibition of platelet activation
Irreversible binding to P2Y12 ADP receptors
Dose-dependent inhibition of platelet aggregation
Aspirin's mechanism of platelet aggregation inhibition
Pharmacokinetics of Clopidogrel
Absorption and Distribution of Clopidogrel
Metabolism and Elimination of Clopidogrel

Dosage & Administration

Recommended dose of 75 mg once daily
No dosage adjustment for elderly patients
Single 300 mg loading dose for acute coronary syndrome
Combination with aspirin
Co-administration with heparin

Interaction

Clopidogrel and aspirin interaction
Clopidogrel and heparin interaction
NSAIDs and Clopidogrel co-administration
Warfarin and Clopidogrel co-administration

Contraindications

Hypersensitivity to the drug substance
Active pathological bleeding

Side Effects

Generally well tolerated

Pregnancy & Lactation

Use during first and second trimesters if needed
Contraindicated during the third trimester
Unknown excretion in human breast milk

Precautions & Warnings

Prolongs the bleeding time
Thrombotic thrombocytopenic purpura (TTP)
Reye's syndrome
Hypersensitivity reactions

Use in Special Populations

Not recommended for children under 12
Aspirin and Reye’s syndrome

Overdose Effects

Bleeding complications with Clopidogrel overdose
Symptoms of moderate Aspirin intoxication
Symptoms of severe Aspirin intoxication
Treatment of Aspirin intoxication

Therapeutic Class

Anti-platelet drugs

Storage Conditions

Cool & dry place below 30°C
Protected from light & moisture
Keep out of reach of children

Related Brands