Clopidol Plus 75 mg+75 mg (Tablet)
Unit Price: ৳ 12.04 (2 x 10: ৳ 240.80)
Strip Price: ৳ 120.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel aspirin |
| Company | Alco pharma ltd |
Indications
- Reduce rate of Myocardial Infarction (MI)
- Reduce rate of Stroke
- Non-ST-segment elevation ACS
- ST-segment elevation ACS
- Unstable angina (UA)
- NSTEMI
- STEMI
- Peripheral Arterial Disease
- Established peripheral arterial disease
- Recent Myocardial Infarction (MI)
- Recent Stroke
Pharmacology
- Prodrug
- Inhibition of platelet activation
- Irreversible binding to P2Y12 class of ADP receptors on platelets
- Dose-dependent inhibition of platelet aggregation
- Inhibition of platelet cyclooxygenase
- Inhibition of thromboxane A2 generation
- Pharmacokinetics
- Metabolism and Elimination
- Absorption and Distribution
Dosage & Administration
- Recommended dose of 75 mg once daily
- No dosage adjustment for elderly patients
- 300 mg loading dose for acute coronary syndrome
- Aspirin in combination with Clopidogrel
- Concurrent use with heparin
Interaction
- Interaction with Aspirin
- Interaction with Heparin
- Interaction with Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
- Interaction with Warfarin
Contraindications
- Hypersensitivity to the drug substance
- Active pathological bleeding
Side Effects
- Generally well tolerated
Pregnancy & Lactation
- Use during first and second trimesters if clearly needed
- Contraindicated during third trimester
- Unknown excretion in human breast milk
Precautions & Warnings
- Prolongs bleeding time
- Thrombotic thrombocytopenic purpura (TTP)
- Reye's syndrome
- Hypersensitivity reactions
Use in Special Populations
- Not recommended for children under 12 years
Overdose Effects
- Bleeding complications
- Platelet transfusion for clotting ability
- Aspirin overdose effects
- Respiratory alkalosis
- Metabolic acidosis
- Hyperthermia
Therapeutic Class
- Anti-platelet drugs
Storage Conditions
- Keep in a cool & dry place below 30°C
- Protected from light & moisture
- Keep out of the reach of children