Xefer 1 gm/20 ml (IV Injection or Infusion)
20 ml vial: ৳ 1,300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ferric carboxymaltose |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of iron deficiency anaemia in adult patients
- Intolerance to oral iron
- Non-dialysis dependent chronic kidney disease
Description
- Colloidal iron (III) hydroxide in complex with Carboxymaltose
- Carbohydrate polymer that releases iron
Dosage & Administration
- Stepwise approach for Ferric Carboxymaltose posology
- Determination of individual iron need
- Calculation and administration of the iron dose(s)
- Post-iron repletion assessments
Interaction
- Formal drug interaction studies not performed with Xefer
Contraindications
- Hypersensitivity to active substance or its excipients
- Hypersensitivity to other parenteral iron products
- Anaemia not attributed to iron deficiency
- Evidence of iron overload or disturbances in iron utilization
Side Effects
- Infrequent, mild, generally do not cause treatment discontinuation
- Common side effects: nausea, headache, dizziness
- Uncommon side effects: hypersensitivity, dysgeusia, tachycardia
- Rare side effects: anaphylactoid reactions, loss of consciousness
Pregnancy & Lactation
- No adequate and well-controlled trials in pregnant women
- Benefit/risk evaluation required before use during pregnancy
- Unlikely risk to the breast-fed child
Precautions & Warnings
- Serious hypersensitivity reactions reported
- Hypertension: transient elevations in systolic blood pressure
- Laboratory Test Alterations: overestimate serum iron and transferrin bound iron by also measuring the iron in Xefer
Use in Special Populations
- Haemodialysis-dependent chronic kidney disease patients: single maximum daily injection dose of 200 mg iron should not be exceeded
- Not recommended in children under 14 years
Overdose Effects
- Excessive dosages may lead to accumulation of iron in storage sites
Therapeutic Class
- Parenteral Iron Preparations
Storage Conditions
- Store in a cool (below 30°C) & dry place
- Keep away from light and do not freeze
- Keep out of the reach of children