Zolvo 200 mg (Tablet)
Unit Price: ৳ 120.00 (1 x 10: ৳ 1,200.00)
Strip Price: ৳ 1,200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Team pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of invasive aspergillosis
- Treatment of candidemia and disseminated candidiasis
- Treatment of esophageal candidiasis
- Treatment of serious infections caused by certain fungal species
- Intolerance or refractory to other therapy
Pharmacology
- Binds and inhibits ergosterol synthesis
- Inhibits CYP450-dependent 14-alpha sterol demethylase
- Results in depletion of ergosterol in fungal cell membrane
Dosage & Administration
- Oral tablet and powder for suspension
- Different dosages based on body weight for oral and injection administration
- Can be taken with or without food depending on the dosage form
- Specific loading dose regimens for different infections
- Maintenance dose regimens for various infections
Interaction
- Adjust dosage and monitor for adverse reactions with CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Potential to increase concentrations and activity of other drugs
- Specific dosage adjustments with co-administration of certain drugs
Contraindications
- Known hypersensitivity to Voriconazole or any other components
- Avoid co-administration with specific drugs due to risk of serious adverse reactions or loss of efficacy
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Should be used during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Long-term exposure requires careful assessment of benefit-risk balance
- Reports of squamous cell carcinoma of the skin with long-term treatment
Use in Special Populations
- Efficacy not established in children under 12 years of age
Overdose Effects
- No specific data available
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for reconstituting the suspension
- Shaking the bottle well before adding water
- Specific volume of water to be added
- Shake vigorously until powder is completely mixed with water
- Storage conditions for reconstituted suspension
Storage Conditions
- Store in a dry place
- Store at specific temperatures
- Protection from light
- Specific storage conditions for powder for suspension