Trivorin 200 mg (Tablet)

Unit Price: ৳ 120.00 (1 x 6: ৳ 720.00)
Strip Price: ৳ 720.00

Medicine Details

Category Details
Generic Voriconazole
Company Somatec pharmaceuticals ltd
Also available as

Category

  • Medicine
  • Antifungal
  • Antimicrobial
  • Treatment

Indication

  • Invasive aspergillosis
  • Candidemia
  • Disseminated candidiasis
  • Esophageal candidiasis
  • Infections caused by Scedosporium apiospermum
  • Infections caused by Fusarium Species
  • Refactory therapy

Pharmacology

  • Triazole antifungal medication
  • Binds and inhibits ergosterol synthesis
  • Inhibits CYP450-dependent 14-alpha sterol demethylase
  • Depletion of ergosterol in fungal cell membrane

Dosage administration

  • Oral intake
  • Loading dose regimen for different body weights
  • Maintenance dose regimen for different body weights
  • Injection for specific indications
  • Dosage adjustment for co-administration with other drugs
  • Oral and intravenous dosage adjustments for specific co-administered drugs

Interaction

  • Inhibition and induction of CYP3A4, CYP2C9, CYP2C19
  • Increase in concentrations and activity of other drugs
  • Dosage adjustment with co-administration of specific drugs

Contraindications

  • Known hypersensitivity to Voriconazole or other drug components
  • Co-administration with specific drugs due to risk of serious adverse reactions
  • Co-administration with specific drugs due to risk of loss of efficacy

Side effects

  • Abdominal pain
  • Anemia
  • Blurred vision
  • Headache
  • Chest pain
  • Nausea
  • Diarrhea

Pregnancy lactation

  • Usage during pregnancy if potential benefit justifies potential risk to fetus
  • No adequate and well-controlled studies in pregnant women

Precautions warnings

  • Careful assessment for long term exposure
  • Reporting of squamous cell carcinoma of the skin related to long-term treatment

Use special populations

  • Efficacy not established for children under 12 years of age

Overdose effects

  • No specific data available

Therapeutic class

  • Other Antifungal preparations

Reconstitution instructions

  • Shake the bottle well before adding water
  • Add specified amount of water to the bottle
  • Mix powder and water thoroughly
  • Store reconstituted suspension between specified temperatures
  • Discard suspension after specified duration

Storage conditions

  • Keep out of reach of children
  • Store in a dry place
  • Store at specified temperature range
  • Store powder for suspension at specified temperature range

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