Floriva-F (25 mcg+250 mcg)/puff (Inhaler)

Indications

• Asthma treatment
• Combination product
• Long-acting β2-agonist
• Inhaled corticosteroid
• As-needed inhaler
• Controlled asthma
• Lung function improvement

Pharmacology

• Selective beta-2 agonist
• Diffuse airway obstruction
• Glucocorticoid activity
• Topical effect on lungs
• Improved lung function
• Convenient regime
• Exo-site binding

Dosage

• For adults and adolescents (12+ years)
• For children (4-12 years)
• Morning and evening dosage
• Inhaler puffs
• Inhalation capsule dosage
• Maxhaler dosage
• Rinsing mouth after inhalation
• Special patient groups

Administration

• Correct inhaler usage
• Shaking before use
• Breathing technique
• Inhalation steps
• Dual inhalation wait time
• Mouth rinsing after use
• Inhaler cleaning instructions

Interaction

• Avoidance of beta-blockers
• Low plasma concentrations
• Strong CYP3A4 inhibitors
• Increased systemic exposure

Contraindications

• Hypersensitivity history
• Primary treatment of status asthmaticus
• Acute asthma episodes

Side Effects

• Beta-2-agonist side effects
• Transient effects
• Cardiac arrhythmia
• Hypersensitivity reactions
• Oropharyngeal irritation
• Muscle cramps
• Hypersensitivity reactions
• Hoarseness
• Candidiasis
• Cutaneous hypersensitivity

Pregnancy & Lactation

• Consideration in pregnancy/lactation
• Insufficient human experience
• Reproductive toxicity in animals
• Low plasma concentrations in breast milk

Precautions & Warnings

• Initiation during exacerbation
• Unstable asthma caution
• Paradoxical bronchospasm
• Increased reporting of pneumonia
• Systemic effects of corticosteroids
• Risk of reduction in growth velocity

Special Populations

• Reduction in growth velocity
• Long-term impact on final height unknown

Overdose Effects

• No human data reported
• Salmeterol overdose symptoms
• Fluticasone Propionate overdose effects
• Temporary suppression of adrenal function
• Chronic overdose effects
• Continuation of therapy after overdose

Therapeutic Class

• Long-acting selective β-adrenoceptor stimulants
• Respiratory corticosteroids

Storage Conditions

• Pressurised canister
• Avoidance of puncturing or incineration
• Storage precautions
• Temperature limits
• Keep away from eyes and children

Related Brands

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