AirFlow 10 mg (Tablet)
Unit Price: ৳ 17.50 (3 x 10: ৳ 525.00)
Strip Price: ৳ 175.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Montelukast sodium |
| Company | Ad din pharmaceuticals ltd |
| Also available as |
Indications
- Prophylaxis and chronic treatment of asthma
- Acute prevention of Exercise-Induced Bronchoconstriction (EIB)
- Relief of symptoms of Allergic Rhinitis (AR): Seasonal & Perennial Allergic Rhinitis
Pharmacology
- Montelukast is a selective and orally active leukotriene receptor antagonist
- Inhibits the cysteinyl leukotriene receptor (CysLT1)
- Correlated with the pathophysiology of asthma & allergic rhinitis
Dosage & Administration
- 10 mg tablet once daily for adults and adolescents 15 years of age and older
- 5 mg tablet once daily for pediatric patients 6 to 14 years of age
- 4 mg tablet once daily for pediatric patients 2 to 5 years of age
- 4 mg oral granules once daily for pediatric patients 6 months to 5 years of age
- No dosage adjustment is required in patients with mild-to-moderate hepatic insufficiency
- No dosage adjustment is recommended in patients with renal insufficiency
- The pharmacokinetic profile and the oral bioavailability of a single 10-mg oral dose of montelukast are similar in elderly and younger adults
- No dosage adjustment in the elderly is required
Interaction
- No apparent increase in adverse reactions when administered with other therapies routinely used in the prophylaxis and chronic treatment of asthma
- No clinically important effects on the pharmacokinetics of certain drugs at the recommended clinical dose
- Used concomitantly with a wide range of commonly prescribed drugs
- Phenobarbital, which induces hepatic metabolism, decreased the AUC of AirFlow approximately 40% following a single 10mg dose
Contraindications
- Montelukast is contraindicated in patients who are hypersensitive to any component of this product
Side Effects
- Common: Diarrhoea, fever, gastrointestinal discomfort, headache, nausea, vomiting, skin reactions, upper respiratory tract infection
- Uncommon: Akathisia, anxiety, arthralgia, asthenia, abnormal behavior, depression, dizziness, drowsiness, dry mouth, haemorrhage, irritability, malaise, muscle complaints, oedema, seizure, abnormal sensation, sleep disorders
- Rare: Angioedema, concentration impaired, disorientation, eosinophilic granulomatosis with polyangiitis, erythema nodosum, hallucination, hepatic disorders, memory loss, palpitations, pulmonary eosinophilia, suicidal tendencies, tremor
Pregnancy & Lactation
- Should be used during pregnancy only if clearly needed
- Caution should be exercised when given to a nursing mother
Precautions & Warnings
- Not indicated for use in the reversal of bronchospasm in acute asthma attacks
- Patients should be advised to have appropriate rescue medication available
- Therapy with AirFlow can be continued during acute exacerbations of asthma
- AirFlow should not be abruptly substituted for inhaled or oral corticosteroids
- Not to be used as monotherapy for the treatment and management of exercise induced bronchospasm
- Patients with known aspirin sensitivity should continue avoidance of aspirin or non-steroidal anti-inflammatory agents while taking AirFlow
Overdose Effects
- No adverse experiences in the majority of overdosage reports
- Adverse experiences consistent with the safety profile of AirFlow
Therapeutic Class
- Leukotriene receptor antagonists
Storage Conditions
- Store in cool & dry place below 30°C
- Protect from light & moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C35H36ClNO3S
- Chemical Structure: See image link for visualization
Common Questions about AirFlow 10 mg Tablet
- Selective and orally active leukotriene receptor antagonist
- Used to treat asthma or allergic rhinitis
- Effect can be observed after 1-3 hours of administration
- Effect lasts for an average duration of 24 hours
- May be taken with or without food as prescribed by doctor
- Avoided in pregnant women unless clearly needed
- General instructions for usage and precautions