Nematox DS 400 mg (Chewable Tablet)

Unit Price: ৳ 5.00 (25 x 2: ৳ 250.00)
Strip Price: ৳ 10.00

Medicine Details

Category Details
Generic Albendazole
Company Chemist laboratories ltd

Product Title

  • Nematox DS

Categories

  • Anthelmintic

Indications

  • Hookworm (Ancylostoma, Necator)
  • Roundworm (Ascaris)
  • Threadworm (Enterobius)
  • Whipworm (Trichuris)
  • Strongyloides
  • Tapeworm
  • Opisthorchi
  • Hydatid

Description

  • Benzimidazole anthelmintic
  • Vermicidal
  • Ovicidal
  • Larvicidal
  • Inhibitory effect on tubulin polymerization
  • Active against most nematodes and some cestodes

Mode of Action

  • Broad spectrum anthelmintic
  • Blocks glucose uptake in susceptible helminths
  • Depletes energy level in helminths
  • Inhibition of parasite tubulin polymerization
  • Extensively metabolized in the liver
  • Poorly absorbed from gastrointestinal tract

Dosage Administration

  • 400 mg single dose for adults & children over 2 years
  • 200 mg single dose for children of 1-2 years
  • Not recommended for children under 1 year
  • 400 mg twice daily for 28 days for Hydatid disease
  • 15 mg/kg body weight daily for patients weighing less than 60 kg
  • 400 mg once daily for five days in giardiasis

Interaction

  • No reported pharmacodynamic or pharmacokinetic interaction

Contraindications

  • Not indicated for neonates
  • Possible reduction of dose in children weighing less than 10 kg
  • Not recommended during pregnancy or lactation
  • No need for dose alteration in renal, hepatic or cardiac failure

Side Effects

  • Gastrointestinal disturbances
  • Headache
  • Dizziness
  • Changes in liver enzymes
  • Reversible alopecia
  • Rare blood disorders including leucopenia and pancytopenia
  • Allergic shock if cyst leakage
  • Convulsion and meningism in cerebral disease

Pregnancy Lactation

  • Category C drug, avoid in pregnancy and lactation

Precautions Warnings

  • Blood counts and liver function tests before treatment and during each cycle
  • Avoid in pregnancy
  • Breastfeeding precautions
  • Constant medical supervision in Echinococcosis treatment

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Keep in dry place, away from light and heat, out of the reach of children

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