Gabarol CR 82.5 mg (Tablet (Controlled Release))

Unit Price: ৳ 25.00 (3 x 10: ৳ 750.00)
Strip Price: ৳ 250.00

Medicine Details

Title

  • Gabarol CR 82.5 mg Tablet

Categories

  • Pain Management
  • Neuropathic Pain Relief
  • Seizure Management

Indications

  • Diabetic Peripheral Neuropathy (DPN)
  • Postherpetic Neuralgia (PHN)
  • Adjunctive Therapy for Partial-Onset Seizures
  • Fibromyalgia
  • Neuropathic Pain Associated with Spinal Cord Injury

Pharmacology

  • Structural Derivative of Gamma-Aminobutyric Acid (GABA)
  • Binds to Alpha2-Delta Site in Central Nervous System Tissues
  • Anti-Nociceptive and Antiseizure Effects

Dosage

  • Maximum Recommended Dose of 100 mg three times a day for DPN
  • Recommended Dose of 75 to 150 mg two times a day for PHN
  • Recommended Dose of 300 to 450 mg/day for Fibromyalgia
  • Recommended Dose Range of 150 to 600 mg/day for Spinal Cord Injury

Administration

  • Oral Route
  • Can be Taken with or Without Food
  • CR Tablet to be Administered after Evening Meal
  • Swallowed Whole, Not to be Split, Crushed, or Chewed
  • Gradual Tapering when Discontinuing

Drug Interaction

  • Unlikely to Involve Significant Pharmacokinetic Interactions
  • No Significant Interactions with Food

Contraindications

  • Hypersensitivity to Pregabalin or any of its Components

Side Effects

  • Common Side Effects in Adults: Dizziness, Somnolence, Dry Mouth, Edema, Blurred Vision, Weight Gain, Difficulty with Concentration/Attention
  • Common Side Effects in Pediatric Patients: Increased Weight, Increased Appetite

Pregnancy & Lactation

  • No Well-Controlled Studies in Pregnant Women
  • Small Amounts Detected in Lactating Women's Milk
  • Breastfeeding Not Recommended due to Potential Risk of Tumorigenicity

Precautions & Warnings

  • Angioedema as Potential Side Effect
  • Risk of Suicidal Thoughts or Behavior
  • Respiratory Depression
  • May Cause Dizziness and Somnolence
  • Increased Seizure Frequency upon Rapid Discontinuation
  • Risk of Peripheral Edema
  • Caution in Coadministration with Thiazolidinedione Antidiabetic Agents

Pediatric Uses

  • Safety and Effectiveness not Established for Various Conditions in Pediatric Patients

Overdose Effects

  • Signs and Symptoms include Reduced Consciousness, Depression/Anxiety, Seizures, Heart Block
  • No Specific Antidote
  • General Supportive Care Indicated

Therapeutic Class

  • Adjunct Anti-Epileptic Drugs
  • Primary Anti-Epileptic Drugs

Storage Conditions

  • Keep in Cool & Dry Place (Below 30°C)
  • Protected from Light & Moisture
  • Keep out of Reach of Children

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image Provided

Commonly Asked Questions

  • Description of Gabarol CR 82.5 mg Tablet
  • Frequency of Use
  • Administration with Food
  • Storage and Disposal Instructions
  • Variation in Action for Different Diseases
  • Duration of Use and Importance of Continuing Even if Feeling Fine
  • Possible Concurrent Use with Diazepam
  • Potential Weight Gain as Side Effect
  • Quick Tips for Usage

Interaction with Medication

Unlikely to be involved in pharmacokinetic drug interactions

Interaction with Food

Not applicable

Management of Fibromyalgia

Recommended dose of 300 to 450 mg/day

Route of Administration

Oral route, CR tablet to be administered after evening meal

Storage and Disposal Instructions

Keep in a cool dry place and in its original packaging. Ensure it remains unreachable to children and pets

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