Gabarol CR 165 mg (Tablet (Controlled Release))
Unit Price: ৳ 35.00 (2 x 10: ৳ 700.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Aci limited |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of 100mg three times a day
- Dosing should begin at 50mg three times a day
- Recommended dose of 75 to 150 mg two times a day for postherpetic neuralgia
- 300 to 450 mg/day for fibromyalgia
- Range of 150 to 600 mg/day for neuropathic pain associated with spinal cord injury
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
Drug Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Not recommended during breastfeeding
Precautions & Warnings
- Angioedema can occur
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur with concomitant CNS depressants
- May cause dizziness and somnolence
Use in Special Populations
- Safety and effectiveness not established in pediatric patients for multiple indications
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Seizures and heart block reported
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
Chemical Structure
- Molecular Formula: C8H17NO2
Commonly Asked Questions
- First-line treatment for neurotic pain, shingles, seizures and fibromyalgia
- Storage instructions and disposal guidelines
- Guidance on frequency and timing of usage