Nabumax 500 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Nabumetone
Company Popular pharmaceuticals ltd
Also available as

Indications

  • Relief of signs and symptoms of osteoarthritis
  • Relief of signs and symptoms of rheumatoid arthritis

Pharmacology

  • Exhibits anti-inflammatory properties
  • Exhibits analgesic properties
  • Exhibits antipyretic properties
  • Mode of action is inhibition of prostaglandin synthesis

Dosage & Administration

  • Available in 500 mg & 750 mg tablets
  • 1000 mg tablet: To be mixed thoroughly in a glass of water and consumed
  • Recommended starting dose is 1000 mg
  • Maximum recommended dose is 2000 mg per day

Interaction

  • May diminish the antihypertensive effect of ACE-inhibitors

Contraindications

  • Contraindicated in patients with known hypersensitivity to nabumetone
  • Not to be given to patients with asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  • Contradicted in peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • Gastrointestinal effects such as diarrhea, dyspepsia, abdominal pain, etc.
  • Central Nervous System effects like dizziness, headache, fatigue, etc.
  • Dermatologic effects including pruritus and rash
  • Special Senses effects like tinnitus
  • Miscellaneous effects like edema

Pregnancy & Lactation

  • Pregnancy Category C
  • Not recommended during the third trimester of pregnancy
  • Not recommended for use in nursing mothers

Precautions & Warnings

  • Associated with renal papillary necrosis and abnormal renal pathology during long-term administration
  • May result in a dose-dependent decrease in prostaglandin synthesis and reduction of renal blood flow
  • Patients at greatest risk are those with impaired renal function, heart failure, liver dysfunction, etc.

Overdose Effects

  • Symptoms may include lethargy, drowsiness, nausea, vomiting, epigastric pain, gastrointestinal bleeding
  • Rare symptoms may include hypertension, acute renal failure, respiratory depression, coma
  • Patients should be managed by symptomatic and supportive care following an overdose
  • No specific antidotes

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs for Rheumatoid Arthritis

Storage Conditions

  • Store in a cool and dry place
  • Keep away from light & moisture
  • Keep all medicines out of reach of children

Chemical Structure

  • Molecular Formula: C15H16O2

Common Questions about Nabumax 500 mg Tablet

  • Used for relieving pain and inflammation
  • Prescribed with food or milk to prevent upset stomach
  • Long-term use may lead to serious complications
  • May cause dizziness, drowsiness, or visual disturbances
  • Avoid consuming alcohol while taking

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