Buflex 750 mg (Tablet)
Unit Price: ৳ 22.00 (2 x 10: ৳ 440.00)
Strip Price: ৳ 220.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Nabumetone |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Relief of signs and symptoms of osteoarthritis
- Relief of signs and symptoms of rheumatoid arthritis
- Consideration of potential benefits and risks before use
- Use of lowest effective dose
- Shortest duration consistent with individual treatment goals
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Mode of action not fully known
- Inhibition of prostaglandin synthesis
Dosage & Administration
- Dosage options: 500 mg, 750 mg, 1000 mg
- Oral administration
- Recommended starting dose: 1000 mg
- Maximum daily doses for different conditions
- Caution in prescribing to patients with renal insufficiency
- Safety and effectiveness not established in pediatric patients
Interaction
- Diminished antihypertensive effect with ACE-inhibitors
- Consideration for patients taking NSAIDs concomitantly with ACE-inhibitors
Contraindications
- Contradiction in patients with known hypersensitivity to nabumetone
- Not to be given to patients with asthma, urticaria, or allergic-type reactions to aspirin or other NSAIDs
- Contraindicated for peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal side effects: Diarrhea, dyspepsia, abdominal pain, constipation
- Central Nervous System side effects: Dizziness, headache, fatigue
- Dermatologic side effects: Pruritus, rash
- Special Senses side effects: Tinnitus
- Miscellaneous side effects: Edema
Pregnancy & Lactation
- Pregnancy Category C
- Use during pregnancy only if dearly needed
- Avoid use during the third trimester of pregnancy
- Not recommended for use in nursing mothers
Precautions & Warnings
- Association with renal papillary necrosis and abnormal renal pathology in animals
- Renal toxicity in patients with conditions leading to reduced renal blood flow or volume
- Discontinuation may lead to recovery to pretreatment state
Overdose Effects
- Symptoms following acute overdose
- Limited symptoms following acute NSAID overdoses
- Possible gastrointestinal bleeding
- Rare occurrences of hypertension, acute renal failure, respiratory depression, and coma
- Symptomatic and supportive care management
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
Storage Conditions
- Cool and dry storage
- Protection from light and moisture
- Keep out of reach of children
Chemical Structure
- Molecular Formula: C15H16O2
Common Questions about Buflex 750 mg Tablet
- Usage as NSAID for anti-inflammatory, analgesic, and antipyretic properties
- Usage for osteoarthritis and rheumatoid arthritis
- Quick tips for usage and precautions