Buflex 500 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Nabumetone
Company Beximco pharmaceuticals ltd
Also available as
Buflex 750 mg tablet Buflex 1000 mg tablet

Title

  • Buflex 500 mg Tablet

Categories

  • NSAID
  • Osteoarthritis Relief
  • Rheumatoid Arthritis Relief

Description

  • Relieves signs and symptoms of osteoarthritis and rheumatoid arthritis
  • Exhibits anti-inflammatory, analgesic, and antipyretic properties
  • Recommended starting dose is 1000 mg taken as a single dose with or without food
  • Can be given in either a single or twice-daily dose
  • Contraindicated in patients with known hypersensitivity to nabumetone or its excipients
  • Symptoms following acute NSAIDs overdoses are usually limited to lethargy, drowsiness, nausea, and vomiting
  • Pregnancy Category C. Use during pregnancy only if dearly needed

Dosage

  • Nabumetone 500 mg & 750 mg Tablet: Oral
  • Nabumetone 1000 mg Tablet: Mix 1 tablet thoroughly in a glass (250 ml) of pure water and drink it completely
  • Recommended starting dose is 1000 mg taken as a single dose with or without food
  • Dosages greater than 2000 mg per day have not been studied
  • Caution should be taken in prescribing Nabumetone to patients with moderate or severe renal insufficiency

Mode of Action

  • Non-steroidal anti-inflammatory drug (NSAID)
  • Inhibits prostaglandin synthesis

Side Effects

  • Gastrointestinal: Diarrhea, dyspepsia, abdominal pain, constipation, flatulence, nausea
  • Central Nervous System: Dizziness, headache, fatigue, increased sweating, insomnia
  • Dermatologic: Pruritus, rash
  • Special Senses: Tinnitus
  • Miscellaneous: Edema

Interaction

  • NSAIDs may diminish the antihypertensive effect of ACE-inhibitors

Contraindications

  • Contraindicated in patients with known hypersensitivity to nabumetone or its excipients
  • Not to be given to patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy only if dearly needed
  • Not recommended for use in nursing mothers

Precautions & Warnings

  • Associated with renal papillary necrosis and other abnormal renal pathology during long-term administration to animals
  • Renal toxicity often associated with conditions leading to a reduction in renal blood flow or blood volume
  • Discontinuation of NSAID therapy is typically followed by recovery to the pretreatment state

Overdose Effects

  • Symptoms include lethargy, drowsiness, nausea, vomiting, and epigastric pain
  • Gastrointestinal bleeding can occur
  • Hypertension, acute renal failure, respiratory depression, and coma may occur but are rare
  • Managed by symptomatic and supportive care following a NSAID overdose
  • Emesis, activated charcoal, and/or osmotic cathartic may be indicated in patients seen within 4 hours of ingestion

Therapeutic Class

  • Osteoarthritis
  • Rheumatoid Arthritis

Storage Conditions

  • Store in a cool and dry place, away from light & moisture

Chemical Structure

  • Molecular Formula: C15H16O2

Common Questions

  • What is Buflex 500 mg Tablet? - NSAID that exhibits anti-inflammatory, analgesic, and antipyretic properties
  • What is Buflex 500 mg Tablet used for? - Osteoarthritis and rheumatoid arthritis relief

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