Caboxen 20 mg (Capsule)

Unit Price: ৳ 355.00 (1 x 90: ৳ 31,950.00)
Strip Price: ৳ 31,950.00

Medicine Details

Category Details
Generic Cabozantinib
Company Everest pharmaceuticals ltd
Also available as
Caboxen 80 mg capsule

Title and Categories

  • Caboxen Medicine Product
  • Oncology
  • Pharmacology
  • Therapeutic Class
  • Storage Conditions

Indications

  • Renal Cell Carcinoma
  • Hepatocellular Carcinoma

Pharmacology

  • Inhibition of MET, VEGFR-1, -2 and -3, AXL, RET, ROS1, TYRO3, MER, KIT, TRKB, FLT-3, and TIE-2
  • Absorption Time (Tmax)
  • Distribution Volume (Vz/F)
  • Protein Binding
  • Metabolism via CYP3A4
  • Excretion and Radioactivity Recovery

Dosage and Administration

  • Recommended Dosage for Renal Cell Carcinoma
  • Recommended Dosage for Hepatocellular Carcinoma
  • Dosage Cautions and Instructions
  • Pediatric Use

Interactions

  • Strong CYP3A4 Inhibitors
  • Strong CYP3A Inducers
  • Grapefruit Interaction
  • St. John's Wort Interaction

Contraindications

  • Known Hypersensitivity

Side Effects

  • Hemorrhage
  • Perforations and Fistulas
  • Thrombotic Events
  • Hypertension and Hypertensive Crisis
  • Diarrhea
  • Palmar-plantar Erythrodysesthesia
  • Proteinuria
  • Osteonecrosis of the Jaw
  • Wound Complications
  • Reversible Posterior Leukoencephalopathy Syndrome

Pregnancy and Lactation

  • Pregnancy Risks
  • Lactation Concerns
  • Contraception Recommendations
  • Females of Reproductive Potential Guidance
  • Infertility Effects

Precautions and Warnings

  • Hemorrhage Management
  • Perforations and Fistulas Monitoring
  • Thrombotic Events Risks
  • Hypertension Monitoring and Management
  • Diarrhea Management
  • Palmar-Plantar Erythrodysesthesia Management
  • Proteinuria Monitoring
  • Osteonecrosis of the Jaw Precautions
  • Wound Complications Cautions
  • Reversible Posterior Leukoencephalopathy Syndrome Evaluation
  • Embryo-Fetal Toxicity Warnings

Overdose Effects

  • Reported Case of Overdosage
  • Recovery Status

Technical Information

  • In vitro Assays Results
  • Single Dose Cmax Increase
  • AUC Observations
  • Terminal Half-life Prediction
  • Clearance Estimate
  • CYP3A4 Substrate
  • Excretion Percentage

Usability

  • Administering Instructions
  • Storage Guidance
  • Child Safety Precautions

Color Options

  • N/A

Dimensions

  • N/A

Materials

  • N/A

Design Elements

  • N/A

Technical Specifications

  • N/A

Functions

  • N/A

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