NFT 100 mg (Capsule (Sustained Release))
Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00
Medicine Details
Category | Details |
---|---|
Generic | Nitrofurantoin |
Company | Healthcare pharmaceuticals ltd |
Also available as |
Indications
- Treatment and prophylaxis of urinary tract infections
- Caused by susceptible strains of Escherichia coli, Enterococci, Staphylococcus aureus, Staphylococcus saprophyticus, Klebsiella, and Enterobacter species
Pharmacology
- Specific for urinary tract infections
- Highly soluble in urine
- Inactivates or alters bacterial ribosomal proteins
- Active against various bacteria including Staphylococcus, Enterococcus, Escherichia coli, Klebsiella, and Citrobacter
Dosage
- Different dosages for adults and children
- Variety of dosage forms including tablets, capsules, and suspension
- Dosage levels for uncomplicated urinary tract infections, long-term suppressive therapy, and prophylaxis
Administration
- Should be taken with food
Interaction
- Reduced absorption when concomitantly administered with antacids containing Magnesium Trisilicate
- Inhibition of renal tubular secretion by Uricosuric drugs such as Probenecid and Sulfinpyrazone
Contraindications
- Anuria, oliguria, or significant impairment of renal function
- Pregnant patients at 38-42 weeks, during labor and delivery
- Known hypersensitivity to Nitrofurantoin
Side Effects
- Frequent adverse events including nausea, headache, and flatulence
- Less common adverse events such as diarrhea, dyspepsia, and abdominal pain
Pregnancy & Lactation
- Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Detected in human breast milk in trace amounts
Precautions & Warnings
- Discontinue if acute, sub-acute, or chronic pulmonary reactions occur
- Avoid antacid preparations containing magnesium trisilicate
Overdose Effects
- Acute overdosage may result in vomiting
- Emesis induction is recommended
Therapeutic Class
- Systemic Urinary Anti-infective
Storage Conditions
- Do not store above 30°C
- Keep away from light and out of the reach of children
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