Vcand 50 mg (Tablet)
Unit Price: ৳ 40.00 (2 x 10: ৳ 800.00)
Strip Price: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Biopharma limited |
| Also available as |
Indications
- Invasive aspergillosis
- Candidemia
- Esophageal candidiasis
- Serious infections caused by Scedosporium apiospermum
- Patients intolerant of other therapy
Pharmacology
- Triazole antifungal medication
- Inhibits ergosterol synthesis
- Binds to and inhibits CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral administration
- Loading dose based on body weight
- Maintenance dose based on body weight
- Injection for invasive aspergillosis and candidemia
- Different dosages for different fungal infections
Interaction
- CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers
- Potential drug interactions with CYP3A4, CYP2C9, and CYP2C19 substrates
- Co-administration with Phenytoin or Efavirenz
Contraindications
- Known hypersensitivity to Voriconazole or any components of the drug
- Co-administration with specific drugs due to risk of serious adverse reactions or loss of efficacy
Side Effects
- Common side effects include abdominal pain, anemia, blurred vision, headache, chest pain, nausea, and diarrhea
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if potential benefit justifies potential risk to the fetus
Precautions & Warnings
- Long-term exposure requires careful assessment of benefit-risk balance
- Reports of squamous cell carcinoma of the skin with long-term treatment
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No available data on overdose effects
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Instructions for reconstituting suspension
- Shake the bottle well before adding water
- Store reconstituted suspension between 15°C-30°C
- Discard reconstituted suspension after 14 days
Storage Conditions
- Keep out of reach of children
- Store in a dry place below 25°C and protected from light
- Store Vcand powder for suspension between 2°C to 8°C