Livocard Plus 75 mg+75 mg (Tablet)
Unit Price: ৳ 12.00 (30's pack: ৳ 360.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel aspirin |
| Company | The white horse pharmaceuticals ltd |
Title
- Livocard Plus
Categories
- Medicine
- Health
- Pharmacy
Description
- Livocard Plus is a medication indicated for reducing the rate of myocardial infarction (MI) and stroke in patients with acute coronary syndrome (ACS), as well as in those with recent MI, recent stroke, or established peripheral arterial disease.
Dimensions
- Standard tablet size
Color Options
- Not applicable
Functions
- Reduces the rate of myocardial infarction and stroke
- Inhibits platelet activation and aggregation
- Irreversible binding to P2Y12 class of ADP receptors on platelets
- Inhibits platelet aggregation through irreversible inhibition of platelet cyclooxygenase
Materials
- Active ingredient: Clopidogrel
Technical Specifications
- Recommended dose: 75 mg once daily
- Loading dose for acute coronary syndrome: 300 mg once
- Plasma concentrations of the metabolite are very low beyond 2 hours after dosing
- Approximately 50% excreted in urine and 46% in feces in 5 days after dosing
Design Elements
- Standard tablet shape
- Protected from light & moisture for storage
Usability Features
- Well tolerated in most individuals
- Should be discontinued during breastfeeding
- May prolong bleeding time
- Has potential risk for Reye's syndrome in children
Pharmacology
- Inhibits platelet aggregation through irreversible binding to P2Y12 class of ADP receptors on platelets
- Irreversible inhibition of platelet cyclooxygenase
- Rapid absorption after oral administration
- Extensively metabolized by the liver
Dosage & Administration
- Recommended dose: 75 mg once daily with or without food
- Loading dose for acute coronary syndrome: 300 mg once
- Combination therapy with aspirin
- No dosage adjustment for elderly or renal patients
Interactions
- Potentiates the effect of aspirin on collagen-induced platelet aggregation
- Associated with increased occult gastrointestinal blood loss when co-administered with NSAIDs
Contraindications
- Hypersensitivity to the drug substance or any component of the product
- Active pathological bleeding such as peptic ulcer or intracranial hemorrhage
Side Effects
- Generally well tolerated
Pregnancy & Lactation
- Use during first and second trimesters if clearly needed
- Contraindicated during the third trimester
- Unknown excretion in human breast milk
Precautions & Warnings
- May prolong bleeding time
- Potential risk for thrombotic thrombocytopenic purpura (TTP) and Reye's syndrome
- Reported hypersensitivity reactions in patients receiving the medication
Use in Special Populations
- Should not be given to children under 12 years unless benefits outweigh risks
- Aspirin may be a contributory factor in the causation of Reye’s syndrome in some children
Overdose Effects
- May lead to bleeding complications
- Symptoms of moderate and severe aspirin intoxication
- Treatment with platelet transfusion and symptomatic care
Therapeutic Class
- Anti-platelet drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children