Vcand 200 mg/5 ml (Powder for Suspension)
40 ml bottle: ৳ 1,000.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Voriconazole |
| Company | Biopharma limited |
| Also available as |
Indications
- Invasive aspergillosis
- Candidemia
- Disseminated candidiasis
- Esophageal candidiasis
- Scedosporium apiospermum infections
- Fusarium Species infections
- Intolerant or refractory to other therapy
Pharmacology
- Triazole antifungal medication
- Inhibition of ergosterol synthesis
- Inhibition of CYP450-dependent 14-alpha sterol demethylase
Dosage & Administration
- Oral administration
- Loading dose based on body weight
- Maintenance dose based on body weight
- Injection for Invasive Aspergillosis, Candidemia, Scedosporiosis, and Fusariosis
Interaction
- CYP3A4, CYP2C9, and CYP2C19 inhibitors and inducers can affect dosage
- May increase concentrations of CYP3A4, CYP2C9, and CYP2C19 substrates
- Increased maintenance dosage with Phenytoin or Efavirenz co-administration
Contraindications
- Hypersensitivity to Voriconazole or components
- Co-administration with specific drugs like terfenadine and rifampin
Side Effects
- Abdominal pain
- Anemia
- Blurred vision
- Headache
- Chest pain
- Nausea
- Diarrhea
Pregnancy & Lactation
- Use during pregnancy only if benefit justifies risk
Precautions & Warnings
- Careful assessment for long term exposure
- Risk of squamous cell carcinoma with long-term treatment
Use in Special Populations
- Efficacy not established for children under 12 years of age
Overdose Effects
- No available overdose data
Therapeutic Class
- Other Antifungal preparations
Reconstitution
- Shake bottle to reconstitute powder for suspension
- Store reconstituted suspension at specific temperatures
- Discard suspension after 14 days of reconstitution
Storage Conditions
- Keep out of reach of children
- Store in dry place below specific temperature
- Store suspension at different temperature range