Copnat-N 0.05% (Cream)

15 gm tube: ৳ 70.00

Medicine Details

Category Details
Generic Clobetasol propionate
Company Renata limited
Also available as

Indications

  • Psoriasis
  • Recalcitrant dermatoses
  • Lichen planus
  • Discoid lupus erythematosus
  • Other skin conditions

Composition

  • Clobetasol Propionate Cream
  • Clobetasol Propionate Ointment
  • Clobetasol Propionate Scalp Application
  • Clobetasol Propionate Shampoo
  • Clobetasol Propionate Lotion
  • Clobetasol Propionate Spray

Pharmacology

Anti-inflammatory, Antipruritic, Vasoconstrictive properties

Dosage

  • Cream
  • Ointment
  • Spray
  • Shampoo
  • Scalp Solution

Administration

Route of administration: Cutaneous. Creams are especially appropriate for moist or weeping surfaces. Ointments are especially appropriate for dry, lichenified or scaly lesions.

Interaction

Co-administered drugs that can inhibit CYP3A4 (e.g. ritonavir, itraconazole) have been shown to inhibit the metabolism of corticosteroids leading to increased systemic exposure.

Contraindications

  • Rosacea
  • Acne vulgaris
  • Perioral dermatitis
  • Hypersensitivity
  • Cutaneous viral infections
  • Primary infected skin lesions
  • Dermatoses in children under one year of age

Side Effects

  • Hypercorticism with prolonged use
  • Local atrophic changes in the skin
  • Pustular form of psoriasis
  • Pigmentation changes
  • Hypertrichosis

Pregnancy & Lactation

Limited data in pregnant women. Caution should be exercised when administered to a nursing woman.

Precautions & Warnings

  • Avoid long-term continuous topical therapy
  • Atrophic changes in the face after prolonged treatment
  • Avoid application on the eyelids
  • Hazardous in psoriasis
  • Use appropriate anti-microbial therapy

Use in Special Populations

  • Avoid long-term continuous therapy in infants and children under 12 years of age
  • Children are more susceptible to developing atrophic changes

Overdose Effects

Acute overdosage is very unlikely to occur. Discontinue in case of chronic over-dosage or misuse.

Therapeutic Class

Other Topical corticosteroids

Storage Conditions

Keep below 30°C, protected from light and moisture. Do not freeze. Keep out of the reach of children.

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