Prebinit 50 mg (Capsule)

Unit Price: ৳ 14.00 (3 x 10: ৳ 420.00)
Strip Price: ৳ 140.00

Medicine Details

Category Details
Generic Pregabalin
Company Genvio pharma ltd
Also available as
Prebinit 25 mg capsule Prebinit 75 mg capsule Prebinit 150 mg capsule

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Binds with high affinity to the alpha2-delta site in central nervous system tissues
  • Anti-nociceptive and antiseizure effects

Dosage

  • Maximum recommended dose of 100 mg three times a day for DPN
  • Maximum recommended dose of 300 mg/day for PHN
  • Recommended dose of 300 to 450 mg/day for fibromyalgia
  • Recommended dose range of 150 to 600 mg/day for spinal cord injury

Administration

  • Oral route of administration
  • Can be taken with or without food
  • Pregabalin CR tablet should be administered after an evening meal
  • Should be swallowed whole and not split, crushed or chewed

Drug interaction

Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention
  • Increased weight and increased appetite in pediatric patients

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Potential risk to a fetus
  • Small amounts detected in the milk of lactating women
  • Breastfeeding not recommended

Precautions & Warnings

  • Risk of angioedema
  • Risk of suicidal thoughts or behavior
  • Potential respiratory depression
  • May cause dizziness and impair ability to drive or operate machinery
  • Caution with coadministering with thiazolidinedione antidiabetic agents

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients for various indications

Overdose Effects

  • Reduced consciousness
  • Depression/anxiety
  • Confusional state
  • Agitation and restlessness
  • Seizures
  • Heart block
  • No specific antidote

Therapeutic Class

  • Adjunct anti-epileptic drugs
  • Primary anti-epileptic drugs

Storage Conditions

Keep in a cool & dry place (below 30°C), protected from light & moisture

Chemical Structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

Common Questions about Prebinit 50 mg Capsule

  • Considered first-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
  • Duration of usage depends on individual's health conditions
  • Prescribed dosage after food
  • Storage in cool dry place, out of reach of children and pets

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