Prebinit 75 mg (Capsule)
Unit Price: ৳ 18.00 (5 x 6: ৳ 540.00)
Strip Price: ৳ 108.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Genvio pharma ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
- Neuropathic pain associated with diabetic peripheral neuropathy in adults (DPN)
- Postherpetic neuralgia in adults (PHN)
- Management of fibromyalgia in adults
- Neuropathic pain associated with spinal cord injury in adults
- Conversion from Pregabalin capsules to Pregabalin CR capsule tablet
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site
- Central nervous system modulation
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of Pregabalin
- Dosing based on creatinine clearance
- Recommended dose for Postherpetic neuralgia
- Recommended dose for Management of fibromyalgia
- Recommended dose range of Pregabalin for Neuropathic pain associated with spinal cord injury
- Conversion from Pregabalin capsules to Pregabalin CR capsule tablet
- Pregabalin tablet total daily dose
- Pregabalin CR capsule dose
Administration
- Route of administration - Oral
- Can be taken with or without food
- Pregabalin CR tablet administration after an evening meal
- Instruction for swallowing Pregabalin CR tablet whole
- Gradual tapering when discontinuing
Interaction
- Unlikely involvement in significant pharmacokinetic drug interactions
- No significant drug interaction with food
- No significant drug interaction with others
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or its components
Side Effects
- Common side effects in adults
- Common side effects in pediatric patients
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Potential risk to a fetus
- Small amounts detected in the milk of lactating women
- Breastfeeding not recommended
Precautions & Warnings
- Risk of angioedema and hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Respiratory depression with concomitant CNS depressants
- Caution for patients operating machinery
- Need for gradual withdrawal
- Potential for peripheral edema
- Caution when coadministering with certain antidiabetic agents
Use in Special Populations
- Safety and effectiveness in pediatric patients
- Safety and effectiveness in pediatric patients below the age of 1 month
- Safety and effectiveness of Prebinit extended-release tablet in pediatric patients
Overdose Effects
- Signs and symptoms of overdose
- No specific antidote
- General supportive care indicated
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Storage in a cool & dry place
- Protection from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula : C8H17NO2
- Chemical Structure Image URL
Common Questions about Prebinit 75 mg Capsule
- Definition of Prebinit 75 mg Capsule
- Duration for improvement in condition
- Frequency of usage
- Instructions for storage and disposal
- Variation in efficacy for different diseases
- Duration of usage
- Need to continue usage even if feeling fine
- Co-administration with Diazepam
- Potential for weight gain
- Quick Tips for usage