Queptam 100 mg (Tablet)
Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00
Medicine Details
Category | Details |
---|---|
Generic | Quetiapine fumarate |
Company | Genvio pharma ltd |
Also available as |
Indications
- Treatment of Acute and chronic psychoses
- Treatment of schizophrenia
- Bipolar Disorder treatment
- Maintenance treatment of bipolar I disorder
- Prevention of recurrence of manic, depressive or mixed episodes
Pharmacology
- Atypical psychotropic agent
- Antagonist at multiple neurotransmitter receptors
- Unknown mechanism of action
- Proposed efficacy through dopamine D2 and serotonin 5HT2 antagonism
- Antagonism of histamine H1 receptors
Dosage & Administration
- Twice daily administration
- First four days dose titration
- Usual effective dose range of 300-450 mg/day
- Dosage adjustment based on clinical response and tolerability
- Initial daily dose for manic episodes associated with bipolar disorder is 100 mg
Interaction
- Caution with medicines causing electrolyte imbalance
- Co-administration with thioridazine or carbamazepine
- Increases in clearance with co-administration of microsomal enzyme inducers like phenytoin
Contraindications
- Hypersensitivity to Quetiapine
Side Effects
- Somnolence
- Dizziness
- Dry mouth
- Elevated serum triglyceride levels
- Decreased HDL cholesterol
- Weight gain
- Extrapyramidal symptoms
Pregnancy & Lactation
- Safety and efficacy not established during human pregnancy
- Use during pregnancy if benefits justify potential risks
- Unknown excretion into human milk
- Advice to avoid breastfeeding while taking Quetiapine
Precautions & Warnings
- Increased risk of suicidal thoughts and self-harm
- Caution in patients with cardiovascular or cerebrovascular disease
- Caution in patients with history of seizures
- Consideration of dose reduction if tardive dyskinesia appears
Use in Special Populations
- Caution in the elderly
- Not indicated for use in children and adolescents below 18 years of age
Overdose Effects
- Survival reported in acute overdoses of up to 30 grams
- No specific antidote
- Intensive care procedures recommended
- Close medical supervision and monitoring
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Keep out of reach of children
- Do not use after expiry date
- Store in a cool and dry place away from light