Queptam 100 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Quetiapine fumarate
Company Genvio pharma ltd
Also available as

Indications

  • Treatment of Acute and chronic psychoses
  • Treatment of schizophrenia
  • Bipolar Disorder treatment
  • Maintenance treatment of bipolar I disorder
  • Prevention of recurrence of manic, depressive or mixed episodes

Pharmacology

  • Atypical psychotropic agent
  • Antagonist at multiple neurotransmitter receptors
  • Unknown mechanism of action
  • Proposed efficacy through dopamine D2 and serotonin 5HT2 antagonism
  • Antagonism of histamine H1 receptors

Dosage & Administration

  • Twice daily administration
  • First four days dose titration
  • Usual effective dose range of 300-450 mg/day
  • Dosage adjustment based on clinical response and tolerability
  • Initial daily dose for manic episodes associated with bipolar disorder is 100 mg

Interaction

  • Caution with medicines causing electrolyte imbalance
  • Co-administration with thioridazine or carbamazepine
  • Increases in clearance with co-administration of microsomal enzyme inducers like phenytoin

Contraindications

  • Hypersensitivity to Quetiapine

Side Effects

  • Somnolence
  • Dizziness
  • Dry mouth
  • Elevated serum triglyceride levels
  • Decreased HDL cholesterol
  • Weight gain
  • Extrapyramidal symptoms

Pregnancy & Lactation

  • Safety and efficacy not established during human pregnancy
  • Use during pregnancy if benefits justify potential risks
  • Unknown excretion into human milk
  • Advice to avoid breastfeeding while taking Quetiapine

Precautions & Warnings

  • Increased risk of suicidal thoughts and self-harm
  • Caution in patients with cardiovascular or cerebrovascular disease
  • Caution in patients with history of seizures
  • Consideration of dose reduction if tardive dyskinesia appears

Use in Special Populations

  • Caution in the elderly
  • Not indicated for use in children and adolescents below 18 years of age

Overdose Effects

  • Survival reported in acute overdoses of up to 30 grams
  • No specific antidote
  • Intensive care procedures recommended
  • Close medical supervision and monitoring

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Keep out of reach of children
  • Do not use after expiry date
  • Store in a cool and dry place away from light

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