Plagrin Plus 75 mg+75 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clopidogrel aspirin |
| Company | Renata limited |
Product Title
- Plagrin Plus
Categories
- Medicine
- Anti-platelet drugs
Description
- Indicated to reduce the rate of Myocardial Infarction (MI) and Stroke
- Recommended dose of 75 mg once daily with or without food
- Combination contraindicated in conditions such as active pathological bleeding and hypersensitivity
- Generally well tolerated
- Unknown excretion in human breast milk
- May prolong bleeding time and lead to TTP and Reye's syndrome
- Not recommended for children under 12 years
- May lead to bleeding complications in overdose
Color Options
- N/A
Dimensions
- N/A
Functions
- Reduces the rate of Myocardial Infarction (MI) and Stroke
- Inhibits platelet activation and aggregation
- Inhibits platelet cyclooxygenase and generation of thromboxane A2
- Rapidly absorbed after oral administration
Materials
- N/A
Technical Specifications
- Recommended dose: 75 mg once daily
- Starting dose for acute coronary syndrome: single 300 mg loading dose and then continued at 75 mg once daily
Design Elements
- Irreversible binding of active metabolite to the P2Y12 class of ADP receptors
- Dose-dependent inhibition of platelet aggregation
- Linear plasma concentrations in the dose range of 50 to 150 mg of Clopidogrel
- Reversible binding in vitro to human plasma proteins
- Rapid hydrolysis into carboxylic acid derivative
Usability Features
- Recommended to be kept in a cool & dry place (below 30°C), protected from light & moisture
Unique Feature 1
- Indicated for non-ST-segment elevation ACS and acute ST-segment elevation ACS
Unique Feature 2
- Inhibition reaches steady state between Day 3 and Day 7
Unique Feature 3
- No dosage adjustment necessary for elderly patients or patients with renal patients
Unique Feature 4
- Binding is nonsaturable up to a concentration of 100 g/mL
Unique Feature 5
- Plasma concentrations increased in proportion to dose in the range of 50 to 150 mg of Clopidogrel
Unique Feature 6
- Approximately 50% excreted in urine and approximately 46% in faeces
Unique Feature 7
- Elimination half-life of the main circulating metabolite is 8 hours after single and repeated administration
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