Corovas 10 mg (Tablet)

Unit Price: ৳ 20.00 (3 x 10: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Indications

  • Reduction of total-C, LDL-C, ApoB, non HDL-C, and TG levels
  • Increase of HDL-C
  • Treatment of hypertriglyceridemia
  • Treatment of dysbetalipoproteinemia
  • Reduction of atherosclerosis progression
  • Pediatric treatment for familial hypercholesterolemia
  • Risk reduction for myocardial infarction, stroke, and arterial revascularization

Pharmacology

  • Selective and competitive inhibitor of HMG-CoA reductase
  • Enhancement of hepatic LDL receptor uptake
  • Inhibition of hepatic VLDL synthesis
  • Reduction of VLDL and LDL particles

Dosage & Administration

  • Usual dose range of 5-20 mg/day
  • Maximum recommended dose of 20 mg/day
  • Specific doses for pediatric, high risk, and homozygous patients
  • Special dosing considerations for Asian patients, concomitant therapy, and severe renal impairment

Interactions

  • Cyclosporine combination increases exposure
  • Gemfibrosil combination should be avoided
  • Lopinavir/Ritonavir or atazanavir/ritonavir combination increases exposure
  • Coumarin anticoagulants prolong international normalized ratio (INR)
  • Potential interactions with lipid-lowering therapies

Contraindications

  • Known hypersensitivity to product components
  • Liver disease with persistent elevated transaminase levels
  • Pregnancy and potential pregnancy
  • Nursing mothers

Side Effects

  • Frequent adverse events include headache, myalgia, constipation, asthenia, abdominal pain, and nausea

Pregnancy & Lactation

  • Administered to women of childbearing age with caution
  • Immediate discontinuation in case of pregnancy
  • Potential excretion in human milk

Precautions & Warnings

  • Caution in patients with predisposing factors for myopathy
  • Potential risk of myopathy with concurrent lipid-lowering therapies
  • Recommended liver enzyme tests before and during therapy
  • Temporary withholding of therapy in case of acute serious conditions

Overdose Effects

  • No specific treatment available
  • Symptomatic and supportive measures recommended
  • Hemodialysis does not significantly enhance clearance

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Temperature below 30°C
  • Protection from light and moisture
  • Keep out of reach of children

Chemical Structure

  • Molecular Formula: C22H28FN3O6S

Common Questions about Corovas 10 mg Tablet

  • Description of the drug and its uses
  • Information about side effects and duration of use
  • Guidance on dosage timing and dietary considerations
  • Tips for monitoring benefits and potential adverse effects
  • Advisory on alcohol consumption and muscle-related problems

Compound Summary

  • Molecular Formula: C22H28FN3O6S

Commonly Asked Questions

  • Description of the drug and its uses
  • Information about side effects and duration of use
  • Guidance on dosage timing and dietary considerations
  • Tips for monitoring benefits and potential adverse effects
  • Advisory on alcohol consumption and muscle-related problems

Related Brands