Abacten 200 mg/5 ml (Powder for Suspension)
30 ml bottle: ৳ 130.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Azithromycin dihydrate |
| Company | Arges life science limited |
| Also available as |
Title
- Abacten 200 mg/5 ml Suspension
Categories
- Antibiotics
- Medication
- Pharmaceuticals
Description
- Indicated for infections in lower respiratory tract
- Indicated for infections in upper respiratory tract
- Indicated for otitis media
- Indicated for skin and soft tissue infections
- Indicated for sexually transmitted diseases
- Pharmacologically stable in acidic conditions
- Readily absorbed
- Absorption is greater on an empty stomach
- Active transport to site of infection
- Large concentrations released during active phagocytosis
- High concentration in tissues
- Half-life allows for large single dose administration
- Bacteriostatic levels maintained for several days
- Plasma clearance of 630 mL/min
- Terminal elimination half-life of 68 hours
- Biliary excretion of azithromycin
- Active against aerobic and facultative gram-positive microorganisms
- Active against aerobic and facultative gram-negative microorganisms
- Active against other microorganisms
- Binds to the 50S ribosomal subunit of susceptible microorganisms
- Interferes with microbial protein synthesis
- Not affecting nucleic acid synthesis
- Oral dosage for adults: 500 mg once daily for 3 days
- Oral dosage for children based on body weight
- Azithromycin injection for adult patient dosage
- Reconstitution procedure for suspension
- Caution with concurrent use of antacids
- Potential pharmacokinetic interaction with carbamazepine
- Potential pharmacokinetic interaction with cyclosporin
- Potential impairment of digoxin metabolism
- Avoid co-administration with ergot derivatives
- No significant effect on methylprednisolone pharmacokinetics
- No evidence of theophylline pharmacokinetic interaction
- No alteration of warfarin anticoagulant effect
- No significant impact on terfenadine pharmacokinetics
- Contraindicated in patients hypersensitive to azithromycin
- Contraindicated in co-administration with ergot derivatives
- Contraindicated in patients with hepatic diseases
- Low incidence of side-effects
- Majority of side-effects gastrointestinal in origin
- Allergic reactions such as rash or photosensitivity
- Reversible elevations in liver transaminases
- Rare cases of cholestatic jaundice observed
- Hearing impairment in investigational studies
- Pregnancy category B
- No evidence of harm to the fetus in animal reproduction studies
- Caution during pregnancy if adequate alternatives are not available
- Unknown secretion in breast milk
- Caution with administration to nursing women
- Risk of serious allergic reactions
- Use in renal impairment
- No dose adjustment needed in patients with mild renal impairment
- Use not recommended in patients with severe renal impairment
- Not recommended in patients with hepatic impairment
- No evidence of effect on patients' ability to drive or operate machinery
- No data on overdosage with Abacten
- Typical symptoms of overdosage with macrolide antibiotics
- No specific data on overdose effects of Abacten
- Storage in a dry place away from light and heat
- Chemical structure: Molecular Formula - C38H72N2O12