GoCal-D 500 mg+200 IU – Price, Uses, and Benefits for Bangladeshi Patients

Category	Details
Generic	Coral calcium vitamin d3
Company	Arges life science limited

Indications

Each tablet contains Calcium Carbonate USP 1250 mg (Coral source) equivalent to 500 mg of elemental Calcium and Vitamin D USP 200 IU
Each DX tablet contains Calcium Carbonate USP 1500 mg (Coral source) equivalent to 600 mg of elemental Calcium and Vitamin D USP 400 IU
Each effervescent tablet contains Calcium Carbonate (Coral source) USP 1500 mg equivalent to 600 mg of elemental Calcium and Vitamin D3 400 IU as Cholecalciferol USP

Adequate Calcium in the blood is vital for various bodily functions
Clinical evidence supports Calcium's usefulness in the prevention and treatment of Osteoporosis and associated fractures
Vitamin D is essential for healthy bones and aids in Calcium absorption from the GI tract
Vitamin D stimulates bone formation
Synergistic effects of Calcium and vitamin D on bone growth, Osteoporosis prevention, and fracture prevention
Coral Calcium sourced from coral origin has better absorption due to its chemical structure
Vitamin D3 aids in Calcium absorption and maintaining Calcium balance in the body

One tablet once or twice daily with plenty of water or as directed by the physician
Effervescent tablet should be dissolved in a glass of water to drink orally, preferably on a full stomach for better absorption

Thiazide diuretics reduce urinary excretion of calcium and require regular serum calcium monitoring
Systemic corticosteroids reduce calcium absorption, may require increased calcium tablet dose
Simultaneous treatment with ion exchange resins or laxatives may reduce gastrointestinal absorption of vitamin D
Calcium carbonate may interfere with the absorption of tetracycline preparations
Hypercalcaemia may increase the toxicity of cardiac glycosides during treatment with calcium and vitamin D
Concomitant use of bisphosphonate or sodium fluoride requires administartion at least three hours before the intake of calcium tablet

Daily intake should not exceed 1500 mg calcium and 600 IU cholecalciferol during pregnancy
Studies in animals have shown reproductive toxicity with high dose of vitamin D
Overdoses of calcium and vitamin D should be avoided in pregnant women
No indications of teratogenicity with therapeutic doses of vitamin D in humans
Calcium and vitamin D3 can be used during pregnancy and breastfeeding, with consideration of vitamin D passing into breast milk

Long-term treatment requires monitoring of serum calcium levels and renal function, especially in elderly patients, patients on concomitant treatment with cardiac glycosides or diuretics, and patients with a tendency to calculus formation
Caution in patients with impaired renal function, and monitoring of calcium and phosphate levels and risk of soft tissue calcification
Caution in patients with severe renal insufficiency, use of other forms of vitamin D
Prescribed with caution in patients suffering from sarcoidosis, with monitoring of serum calcium levels and urinary calcium excretion
Caution in immobilised patients with osteoporosis due to the increased risk of hypercalcaemia
Consideration of the dose of vitamin D when prescribing other drugs containing vitamin D, additional doses under close medical supervision

Hypervitaminosis D and hypercalcaemia
Symptoms of hypercalcaemia may include anorexia, thirst, nausea, vomiting, constipation, abdominal pain, muscle weakness, fatigue, mental disturbances, polydipsia, polyuria, bone pain, nephrocalcinosis, nephrolithiasis, and in severe cases, cardiac arrhythmias
Persistently high calcium levels may lead to irreversible renal damage and soft tissue calcification
Discontinuation of treatment with calcium and other concomitant drugs
Rehydration and isolated or combined treatment with loop diuretics, bisphosphonates, calcitonin, and corticosteroids

GoCal-D 500 mg Tablet is a combination of calcium carbonate and vitamin D3. It is used to prevent and treat calcium and vitamin D deficiency. Calcium is important for building and maintaining strong bones and teeth. Vitamin D helps the body absorb calcium
Benefits include prevention and treatment of calcium and vitamin D deficiency, osteoporosis prevention, treatment of rickets, treatment of osteomalacia, and improvement of bone health in the elderly
Contraindications include high level of calcium or vitamin D in the blood, kidney stones, sarcoidosis, and being allergic to ingredients in Coralcal D
Common side effects are constipation, nausea, vomiting, diarrhea, headache, drowsiness, and dry mouth
Tablet should be taken with food, and the dosage may vary depending on individual needs
Precautions include not taking the tablet during pregnancy or breastfeeding, with high levels of calcium or vitamin D, and presence of kidney stones or allergy to any of the ingredients