Soltara 200 mg (Tablet)

Unit Price: ৳ 6.00 (30's pack: ৳ 180.00)

Medicine Details

Category	Details
Generic	Doxophylline
Company	Arges life science limited

Doxophylline is a novel bronchodilator
Structurally differs from Theophylline due to the presence of a dioxolane group in position 7
Selectively inhibits phosphodiesterase 4
Relaxes bronchial smooth muscle
Decreased affinities toward adenosine A1 and A2 receptors
Reported to inhibit platelet activating factor (PAF) and generation of leukotriene production

Elderly: 200 mg tablet two or three times daily
Adults: 400 mg tablet two or three times daily or as prescribed by the physician
Children: >12 years of age: 10 ml syrup or 200 mg tablet two or three times daily
6-12 years of age: 6-9 mg/kg body weight two times daily
If required daily dose of Doxophylline is 400 mg, Doxophylline SR tablet to be taken once daily or as prescribed by the physician

Should not be administered with other xanthine preparations
Limit consumption of beverages and food containing caffeine
Caution in administering Soltara together with ephedrine or other sympathomimetic drugs
Concurrent administration of drugs such as erythromycin, TAO, lincomycin, clindamycin, allopurinol, cimetidine, influenza vaccine and propanolol may reduce the hepatic clearance of xanthine derivatives
Phenytoin, other anticonvulsants and cigarette smoking may increase the clearance of xanthine derivatives

Animal tests have shown that the active ingredient of Doxophylline does not interfere with pre and postnatal growth
Insufficient clinical evidence about the effects of the drug during pregnancy
Use of the drug during pregnancy should be evaluated carefully case by case on the basis of the risk-benefit ratio
Contraindicated during lactation

Factors that may reduce the hepatic clearance of xanthine derivatives
Age, congestive cardiac decompensation, chronic obstructive pulmonary disease
Severe liver disease, concomitant infections
Concurrent administration of several drugs such as erythromycin, TAO, lincomycin, clindamycin, allopurinol, cimetidine, influenza vaccine and propanolol
Caution in administering the product to patients with cardiac disease, hypertension, in the elderly, severe hypoxemia, hyperthyroidism, chronic corpulmonale, congestive heart failure, liver disease, peptic ulcer, renal impairment

Severe cardiac arrhythmias
Tonic-clonic seizure may occur
First signs of intoxication
No specific antidote, symptomatic treatment of cardiovascular collapse should be instituted