Debac 500 mg (Capsule)

Unit Price: ৳ 10.00

Medicine Details

Category Details
Generic Flucloxacillin sodium
Company Fnf pharmaceuticals ltd

Indications

  • Skin and soft tissue infections
  • Respiratory tract infections
  • Osteomyelitis treatment
  • Enteritis treatment
  • Urinary tract infection treatment
  • Meningitis treatment
  • Septicaemia treatment
  • Prophylactic use during major surgical procedures

Pharmacology

  • Active against Gram-positive organisms
  • Little activity against Gram-negative bacilli
  • Inhibits the formation of bacterial cell wall
  • Bactericidal antibiotic
  • Useful against penicillinase-producing staphylococci
  • Interferes with peptidoglycan synthesis

Dosage

  • Oral administration for adults: 250 mg four times daily
  • Severe infections may require doubled dosage
  • Intramuscular Injection for adults: 250 mg four times daily
  • Intravenous injection for adults: 250 mg-1 g four times daily
  • Children dosage: 1/2 of adult dose for 2-10 years and 1/4 for under 2 years

Administration

  • Oral doses should be administered 1 hour before meal

Interaction

  • Concurrent use may result in increased level in blood

Contraindications

  • Contraindicated in penicillin hypersensitive patients

Side Effects

  • Common side effects: nausea, vomiting, diarrhea, dyspepsia
  • Other reported side effects: rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis, cholestatic jaundice

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Caution should be exercised during lactation

Precautions & Warnings

  • Use with caution in patients with hepatic dysfunction
  • Caution in allergic diathesis

Use in Special Populations

  • Consider dose reduction in severe renal failure

Therapeutic Class

  • Penicillinase-resistant penicillins

Reconstitution

  • Used in other routes in conjunction with systemic therapy
  • Administered by intraarticular and intrapleural injection
  • Administered by nebuliser

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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