Debac 500 mg (Capsule)
Unit Price: ৳ 10.00
Medicine Details
Category | Details |
---|---|
Generic | Flucloxacillin sodium |
Company | Fnf pharmaceuticals ltd |
Indications
- Skin and soft tissue infections
- Respiratory tract infections
- Osteomyelitis treatment
- Enteritis treatment
- Urinary tract infection treatment
- Meningitis treatment
- Septicaemia treatment
- Prophylactic use during major surgical procedures
Pharmacology
- Active against Gram-positive organisms
- Little activity against Gram-negative bacilli
- Inhibits the formation of bacterial cell wall
- Bactericidal antibiotic
- Useful against penicillinase-producing staphylococci
- Interferes with peptidoglycan synthesis
Dosage
- Oral administration for adults: 250 mg four times daily
- Severe infections may require doubled dosage
- Intramuscular Injection for adults: 250 mg four times daily
- Intravenous injection for adults: 250 mg-1 g four times daily
- Children dosage: 1/2 of adult dose for 2-10 years and 1/4 for under 2 years
Administration
- Oral doses should be administered 1 hour before meal
Interaction
- Concurrent use may result in increased level in blood
Contraindications
- Contraindicated in penicillin hypersensitive patients
Side Effects
- Common side effects: nausea, vomiting, diarrhea, dyspepsia
- Other reported side effects: rashes, urticaria, purpura, fever, interstitial nephritis, hepatitis, cholestatic jaundice
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Caution should be exercised during lactation
Precautions & Warnings
- Use with caution in patients with hepatic dysfunction
- Caution in allergic diathesis
Use in Special Populations
- Consider dose reduction in severe renal failure
Therapeutic Class
- Penicillinase-resistant penicillins
Reconstitution
- Used in other routes in conjunction with systemic therapy
- Administered by intraarticular and intrapleural injection
- Administered by nebuliser
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children