Brocef CV 500 mg+125 mg (Tablet)

Unit Price: ৳ 60.00 (1 x 8: ৳ 480.00)
Strip Price: ৳ 480.00

Medicine Details

Category Details
Generic Cefuroxime axetil clavulanic acid
Company Gaco pharmaceuticals ltd
Also available as
Brocef cv 250 mg tablet

Product Title

Brocef Plus 500 mg Tablet

Categories

  • Antibiotic
  • Medication
  • Pharmaceutical

Description

Brocef Plus is indicated for the treatment of various bacterial infections caused by sensitive bacteria. It contains Cefuroxime, a second generation cephalosporin antibiotic, and Clavulanic acid, a beta-lactamase inhibitor.

Dosage Form

Tablet

Dosage Strength

500 mg

Indications

  • Pharyngitis/Tonsillitis
  • Acute Bacterial Otitis Media
  • Acute bacterial maxillary sinusitis
  • Lower respiratory tract infections
  • Uncomplicated skin and skin-structure infections
  • Uncomplicated urinary tract infections
  • Bone and Joint Infections
  • Uncomplicated Gonorrhoea
  • Early Lyme Disease (erythema migrans)
  • Septicemia
  • Meningitis
  • Switch therapy (Injectable to oral)

Pharmacology

Cefuroxime inhibits bacterial cell wall synthesis by interfering with the transpeptidation process. Clavulanic acid protects Cefuroxime from degradation by beta lactamase enzymes and provides a solution for the treatment of bacterial infections caused by beta lactam resistant bacteria.

Dosage and Administration

  • Adolescents and adults (13 years and older):
    • Pharyngitis/tonsillitis: 250 mg b.i.d. for 5-10 days
    • Acute bacterial maxillary sinusitis: 250 mg b.i.d. for 10 days
    • Acute bacterial exacerbation of chronic bronchitis: 250-500 mg b.i.d. for 10 days
    • Secondary bacterial infections of acute bronchitis: 250-500 mg b.i.d. for 5-10 days
    • Uncomplicated skin and skin structure infections: 250-500 mg b.i.d. for 10 days
    • Uncomplicated urinary tract infections: 250 mg b.i.d. for 7-10 days
    • Uncomplicated Gonorrhoea: 1000 mg b.i.d. Single dose
    • Community acquired pneumonia: 250-500 mg b.i.d. for 5-10 days
    • MDR Typhoid Fever: 500 mg b.i.d. for 10-14 days
    • Early Lyme disease: 500 mg b.i.d. for 20 days
  • Paediatric Patients (3 months to 12 years):
    • Pharyngitis/Tonsillitis: 20 mg/kg/day b.i.d for 5-10 days
    • Acute otitis media: 30 mg/kg/day b.i.d for 10 days
    • Acute bacterial maxillary sinusitis: 30 mg/kg/day b.i.d for 10 days
    • Impetigo: 30 mg/kg/day b.i.d for 10 days

Interaction

Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%. Drug that reduces gastric acidity may result in a lower bioavailability of Cefuroxime and tend to cancel the effect of postprandial absorption.

Contraindications

  • Patients with known allergy to cephalosporin
  • Patients with Pseudomembranous Colitis

Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Overgrowth of nonsusceptible microorganisms
  • Renal dysfunction
  • Anaphylaxis
  • Angioedema
  • Pruritis
  • Rash
  • Serum sickness like urticaria

Pregnancy & Lactation

Cefuroxime-Clavulanic Acid can be safely used in later pregnancy to treat urinary and other infections. It is excreted into the breast milk in small quantities, hence sensitizing the infant should be kept in mind.

Precautions & Warnings

Cefuroxime should be given with care to patients receiving concurrent treatment with potent diuretics and who has a history of colitis.

Therapeutic Class

Second generation Cephalosporins

Storage Conditions

Store in a cool, dry place (below 30°C), away from light and moisture. Keep out of the reach of children.

Commonly Asked Questions

  • What is Brocef Plus 500 mg Tablet?
  • What is Brocef Plus 500 mg Tablet used for?
  • How long does it take for Brocef Plus 500 mg Tablet to take effect?
  • How long do the effects of this medicine last?
  • Is Brocef Plus 500 mg Tablet safe to consume alcohol while taking this medicine?
  • Is Brocef Plus 500 mg Tablet a habit forming medicine?
  • Can this medicine be taken during pregnancy?
  • Can Brocef Plus 500 mg Tablet be taken while breast-feeding?
    • Quick Tips:
      • You have been prescribed Brocef Plus 500 mg Tablet medicine to treat bacterial infections, even if they have developed resistance.
      • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
      • Take it with food to avoid an upset stomach.
      • Diarrhea may occur as a side effect. Taking probiotics may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps.
      • Stop taking Brocef Plus 500 mg Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue, or breathing difficulties while taking it.
      • Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic.

Related Brands