Zesprin 75 mg+75 mg (Tablet)

Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00

Medicine Details

Category Details
Generic Clopidogrel aspirin
Company Zenith pharmaceuticals ltd

Indications

  • Reduce rate of Myocardial Infarction (MI)
  • Reduce rate of Stroke
  • Non-ST-segment elevation ACS
  • ST-segment elevation ACS
  • Recent MI
  • Recent Stroke
  • Established Peripheral Arterial Disease

Pharmacology

  • Inhibits platelet activation
  • Inhibits platelet aggregation
  • Irreversible binding of active metabolite
  • Dose-dependent inhibition of platelet aggregation
  • Inhibition of platelet cyclooxygenase
  • Inhibition of thromboxane A2 generation
  • Pharmacokinetics: plasma concentrations, metabolism, elimination
  • Absorption and distribution
  • Metabolism and elimination

Dosage & Administration

  • Recommended dose: 75 mg once daily
  • Can be taken with or without food
  • Elderly patients dosage adjustment not necessary
  • Loading dose for acute coronary syndrome: 300 mg
  • Combination with Aspirin
  • Studies on patients with acute coronary syndrome

Interaction

  • Aspirin interaction
  • Heparin interaction
  • NSAIDs interaction
  • Warfarin interaction

Contraindications

  • Hypersensitivity to the drug substance
  • Active pathological bleeding

Side Effects

  • Generally well tolerated

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Use during first and second trimesters if clearly needed
  • Contraindicated during the third trimester
  • Excretion in human breast milk
  • Discontinuation during breastfeeding

Precautions & Warnings

  • May prolong bleeding time
  • Thrombotic thrombocytopenic purpura (TTP)
  • Reye's syndrome
  • Hypersensitivity
  • History of hypersensitivity

Use in Special Populations

  • Not to be given to children under 12 years
  • Expected benefits outweigh possible risks

Overdose Effects

  • Bleeding complications
  • Moderate Aspirin intoxication
  • Severe Aspirin intoxication

Therapeutic Class

  • Anti-platelet drugs

Storage Conditions

  • Keep in a cool & dry place (below 30°C)
  • Protected from light & moisture
  • Keep out of the reach of children

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