Pulmidone 801 mg (Tablet)

Unit Price: ৳ 125.00 (1 x 10: ৳ 1,250.00)
Strip Price: ৳ 1,250.00

Medicine Details

Category Details
Generic Pirfenidone
Company Beximco pharmaceuticals ltd
Also available as
Pulmidone 267 mg tablet

Indications

  • Treatment of mild to moderate Idiopathic Pulmonary Fibrosis (IPF)

Pharmacology

  • Anti-inflammatory properties
  • Antioxidant properties
  • Anti-fibrotic properties
  • Improves lung function
  • Reduces acute exacerbations
  • Suppresses TGF-β1
  • Downregulates pro-inflammatory cytokines
  • Inhibits inflammatory cell influx
  • Reduces pulmonary vascular permeability

Dosage & Administration

  • Oral administration with food
  • Titration dose schedule
  • Dosage adjustments for gastrointestinal events
  • Dosage adjustments for photosensitivity reaction or rash
  • Dosage adjustments for hepatic function
  • Treatment interruption guidelines

Interaction

  • Moderate and strong inhibitors of CYP1A2 impact
  • Recommendations with food intake
  • Dose adjustments with specific medications

Contraindications

  • Hypersensitivity to active substance or excipients
  • Concomitant use of fluvoxamine
  • Severe hepatic impairment or end-stage liver disease
  • Severe renal impairment or end-stage renal disease

Side Effects

  • Common side effects: nausea, rash, abdominal pain, etc.
  • Rare side effects: photosensitivity reaction, decreased appetite, etc.

Pregnancy & Lactation

  • Precautionary avoidance during pregnancy
  • Unknown excretion in human milk
  • Effects on fertility and reproductive performance in animals

Precautions & Warnings

  • Monitoring of liver enzymes
  • Avoidance of photosensitivity and rash triggers
  • Management of gastrointestinal disorders

Use in Special Populations

  • Safety and effectiveness in children & adolescents
  • Considerations for hepatic impairment
  • Considerations for renal impairment
  • Effects on smokers

Overdose Effects

  • Limited clinical experience with overdose
  • Information on mild and transient adverse reactions for overdose doses

Therapeutic Class

  • Immunosuppressant

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Safety measures to keep out of reach of children

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