Kof-free (100 mg+1.1 mg+14 mg)/5 ml (Syrup)

100 ml bottle: ৳ 85.00

Medicine Details

Indications

  • Relief of cough
  • Relief of associated congestive symptoms
  • Aiding restful sleep

Composition

  • Guaifenesin BP 100 mg
  • Levomenthol BP 1.1 mg
  • Diphenhydramine Hydrochloride BP 14 mg

Pharmacology

  • Guaifenesin reduces viscosity of sputum
  • Levomenthol has local anesthetic properties
  • Diphenhydramine Hydrochloride is antitussive, antihistaminic, and anticholinergic

Dosage & Administration

  • 2 teaspoonfuls syrup 4 times a day for adults and children over 12 years
  • Not more than 8 teaspoonful syrup in 24 hours
  • Efficacy and safety not established in pediatric patients and adolescents

Interaction

  • Potentiates effects of alcohol and CNS depressants
  • Potentiates effects of anticholinergics
  • May result in tachycardia, dry mouth, gastrointestinal disturbances, urinary retention, and headache

Contraindications

  • Hypersensitivity to the product or its components
  • Recent treatment with MAOIs
  • Narrow-angle glaucoma or symptomatic prostatic hypertrophy

Side Effects

  • Drowsiness
  • Dizziness
  • Nausea and vomiting
  • Gastrointestinal disturbance
  • Dry mouth, nose, and throat
  • Difficulty in urination
  • Blurred vision

Pregnancy & Lactation

  • Care should be taken during pregnancy
  • No adverse effects in human fetus or suckling infant

Precautions & Warnings

  • May cause drowsiness
  • Should not be taken by individuals with narrow-angle glaucoma or symptomatic prostatic hypertrophy
  • Not for persistent or chronic cough without physician's direction

Overdose Effects

  • Excess Guaifenesin may cause renal calculi
  • Treatment should be symptomatic and supportive

Therapeutic Class

  • Combined cough expectorants

Storage Conditions

  • Store at a temperature not exceeding 30°C
  • In a dry place
  • Protect from light and moisture
  • Keep out of the reach of children

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