Esogel 40 mg/vial (IV Injection)

40 mg vial: ৳ 90.00

Medicine Details

Category Details
Generic Esomeprazole
Company Novatek pharmaceuticals ltd
Also available as
Esogel 20 mg capsule Esogel 40 mg capsule Esogel 20 mg tablet Esogel 40 mg tablet

Indications

  • Relief from chronic heartburn symptoms
  • Healing of erosive esophagitis
  • Maintenance of healing of erosive esophagitis
  • Eradication of Helicobacter pylori infection
  • Zollinger-Ellison Syndrome
  • Acid-related Dyspepsia
  • Duodenal & Gastric ulcer

Pharmacology

  • Proton pump inhibitor
  • Suppression of gastric acid secretion
  • Absorption dynamics
  • Distribution in plasma proteins
  • Metabolism by CYP enzymes
  • Excretion details
  • Combination therapy with antimicrobials

Dosage

  • Healing of Erosive Esophagitis: 20 mg or 40 mg Once Daily for 4-8 Weeks
  • Maintenance of Healing of Erosive Esophagitis: 20 mg Once Daily
  • Symptomatic GERD: 20 mg Once Daily for 4 Weeks
  • Helicobacter Pylori eradication: Triple Therapy
  • Zollinger-Ellison Syndrome: 20-80 mg once daily
  • Acid-related Dyspepsia: 20-40 mg once daily
  • Duodenal ulcer: 20 mg once daily
  • IV Injection: Dosage by patient's age and condition

Administration

  • Tablet or capsule should be swallowed whole and taken one hour before a meal
  • Oral Suspension
  • IV Injection
  • IV Infusion

Interaction

  • Extensive metabolism in the liver by CYP2C19 and CYP3A4
  • Potential interference with CYP2C19
  • Inhibition of gastric acid secretion affecting drug absorption
  • Specific interactions with certain drugs

Contraindications

  • Known hypersensitivity to any of the formulations

Side Effects

  • Headache
  • Diarrhea
  • Nausea
  • Flatulence
  • Abdominal pain
  • Constipation
  • Dry mouth

Pregnancy & Lactation

  • No adequate and well-controlled studies in pregnant women
  • Animal studies revealed no teratogenic effects
  • Excretion in milk not studied
  • Breastfeeding should be discontinued if essential

Precautions & Warnings

  • Symptomatic response does not preclude the presence of gastric malignancy
  • Detailed instructions for patients with swallowing difficulty
  • Use of antacids while taking Esogel

Use in Special Populations

  • Safety and effectiveness in paediatric patients not established
  • No overall differences in safety and efficacy in the elderly
  • Dosage adjustment recommendations for hepatic insufficiency
  • Expected pharmacokinetics in renal impairment

Overdose Effects

  • Toxicity signs in animal studies
  • No specific antidote known
  • Symptomatic and supportive treatment recommended

Storage Conditions

  • Temperature and environmental storage instructions

Chemical Structure

  • Molecular Formula: C17H19N3O3S
  • Chemical Structure Image

Common Questions

  • Uses and working mechanism of Esogel 40 mg/vial Injection
  • Common side effects
  • Safety concerns during pregnancy and breastfeeding
  • Onset of action
  • Quick tips for dosage and precautions

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