Dinakion MM 2 mg/0.2 ml (Injection)

Indications

• Prophylaxis and treatment of haemorrhagic disease in the newborn
• Haemorrhage or risk of haemorrhage as a result of severe hypoprothrombinemia
• Prevention and treatment of bleeding due to vitamin K deficiency

Pharmacology

• Procoagulant factor
• Involved in the post translational carboxylation of clotting factors II (prothrombin), VII, IX and X
• Promotes synthesis of coagulation factors by the liver

Dosage & Administration

• 2 mg orally at or just after birth for neonates
• 5-10 mg orally for children over 1 year of age
• 1 mg by intravenous injection initially for therapy
• Special dosage for neonates with risk factors
• Administered orally following the dosing schedule for total protection of newborns

Interaction

• Antagonises the effect of coumarin-type anticoagulants
• Coadministration of anticonvulsants can impair the action of vitamin K-1

Contraindications

• Known hypersensitivity to any of its constituents

Side Effects

• Possible occurrence of anaphylactoid reactions
• Venous irritation or phlebitis after parenteral use of Dinakion MM injections

Precautions & Warnings

• Careful monitoring of coagulation parameters is necessary for patients with severely impaired liver function after administration of Dinakion MM

Therapeutic Class

• Vitamin-K Preparations

Storage Conditions

• Keep below 30°C temperature
• Keep away from light & moisture
• Keep out of the reach of children

Related Brands

• Babykion 2 mg/0.2 ml (Injection) - chemist-laboratories-ltd
• Dinakion 10 mg/ml (Injection) - drug-international-ltd