Neurovan 150 mg (Capsule)

Indications

• Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
• Postherpetic neuralgia (PHN)
• Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
• Fibromyalgia
• Neuropathic pain associated with spinal cord injury

Pharmacology

• Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
• Binds with high affinity to the alpha2-delta site in central nervous system tissues

Dosage

• Maximum recommended dose of Pregabalin is 100 mg three times a day (300 mg/day) for DPN in adults with creatinine clearance of at least 60 ml/min
• Recommended dose of Pregabalin is 75 to 150 mg two times a day or 50 to 100 mg three times a day (150 to 300 mg/day) for PHN in adults with creatinine clearance of at least 60 ml/min
• Recommended dose of Pregabalin is 300 to 450 mg/day for fibromyalgia in adults
• Recommended dose range of Pregabalin is 150 to 600 mg/day for neuropathic pain associated with spinal cord injury in adults

Administration

• Route of administration: oral
• Pregabalin CR tablet should be administered after an evening meal
• Should be swallowed whole and should not be split, crushed or chewed

Interaction

• Neurovan is unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

• Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components

Side Effects

• Most common side effects in adults: dizziness, somnolence, dry mouth, edema, blurred vision, weight gain and thinking abnormal
• Most common side effects in pediatric patients for the treatment of partial onset seizures: increased weight and increased appetite

Pregnancy & Lactation

• No adequate and well-controlled studies with pregabalin in pregnant women
• Breastfeeding is not recommended during treatment with pregabalin

Precautions & Warnings

• Angioedema can occur and may be associated with life threatening respiratory compromise
• Antiepileptic drugs, including Neurovan, increase the risk of suicidal thoughts or behavior
• Neurovan may cause dizziness and somnolence and impair patients ability to drive or operate machinery

Use in Special Populations

• Safety and effectiveness in pediatric patients have not been established for various uses

Overdose Effects

• Signs and symptoms: reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures and heart block

Therapeutic Class

• Adjunct anti-epileptic drugs
• Primary anti-epileptic drugs

Storage Conditions

• Keep in a cool & dry place (below 30°C), protected from light & moisture

Chemical Structure

• Molecular Formula: C8H17NO2

Common Questions about Neurovan 150 mg Capsule

• An anticonvulsant and is considered to be the first-line of treatment for neurotic pain, shingles, seizures and fibromyalgia
• To be taken till the time improvement in health conditions is observed
• Should be taken after food in a prescribed dosage
• Should be kept in a cool dry place and in its original packaging

Related Brands

• GABA-P 50 mg (Capsule) - renata-limited
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• Gabarol 50 mg (Capsule) - aci-limited
• Gabarol 75 mg (Capsule) - aci-limited