Neurolin CR 82.5 mg (Tablet (Controlled Release))
Unit Price: ৳ 25.00 (1 x 10: ৳ 250.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Square pharmaceuticals plc |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Maximum recommended dose of Pregabalin is 100 mg three times a day for adults with DPN
- Recommended dose of Pregabalin is 75 to 150 mg two times a day for adults with PHN
- Recommended dose of Pregabalin for the management of fibromyalgia in adults is 300 to 450 mg/day
- Recommended dose range of Pregabalin for neuropathic pain associated with spinal cord injury is 150 to 600 mg/day
Administration
- Oral route of administration
- Can be taken with or without food
- Pregabalin CR tablet should be administered after an evening meal
- Should be swallowed whole and should not be split, crushed, or chewed
Interaction
- Drug interaction with medication: Unlikely to be involved in significant pharmacokinetic drug interactions
- Drug interaction with food and others: Not applicable
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Most common side effects in adults:
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal
- Most common side effects in pediatric patients:
- Increased weight
- Increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies with pregabalin in pregnant women
- Small amounts of pregabalin have been detected in the milk of lactating women
- Breastfeeding is not recommended during treatment with pregabalin due to the potential risk of tumorigenicity
Precautions & Warnings
- Angioedema may occur
- Hypersensitivity reactions should lead to immediate discontinuation
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- May cause dizziness, somnolence, and impair patients' ability to drive or operate machinery
- Increased seizure frequency or other adverse reactions may occur if rapidly discontinued
- May cause peripheral edema
Use in Special Populations
Safety and effectiveness not established for pediatric patients below the age of 1 month
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Agitation
- Restlessness
- Seizures
- Heart block
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure Image: URL to chemical structure image
Common Questions
- What is Neurolin CR 82.5 mg CR Tablet?
- How long do I need to use Neurolin CR 82.5 mg CR Tablet before I see improvement in my condition?
- At what frequency do I need to use Neurolin CR 82.5 mg CR Tablet?
- Should I use Neurolin CR 82.5 mg CR Tablet empty stomach, before food or after food?
- What are the instructions for the storage and disposal of Neurolin CR 82.5 mg CR Tablet?
- Does Neurolin CR 82.5 mg CR Tablet work in the same way for each disease?
- How long do I need to take Neurolin CR 82.5 mg CR Tablet?
- Is it necessary to continue taking Neurolin CR 82.5 mg CR Tablet even if I feel fine?
- Can I take Diazepam and Neurolin CR 82.5 mg CR Tablet together?
- Can the use of Neurolin CR 82.5 mg CR Tablet cause weight gain?
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