Prelin 100 mg (Capsule)
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Drug international ltd |
| Also available as |
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It binds with high affinity to the alpha2-delta site in central nervous system tissues, which may be involved in its anti-nociceptive and antiseizure effects.
Dosage
Recommended doses for various conditions including neuropathic pain, postherpetic neuralgia, fibromyalgia, and spinal cord injury.
Administration
- Route of administration: Oral
- Administration instructions: Should be swallowed whole and should not be split, crushed or chewed. Pregabalin CR tablet should be administered after an evening meal.
Interaction
- Drug interaction with medication: Unlikely to be involved in significant pharmacokinetic drug interactions
- Drug interaction with food and others: Not applicable
Contraindications
Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Thinking abnormal
Pregnancy & Lactation
- Pregnancy: No adequate and well-controlled studies with pregabalin in pregnant women. Pregnant women should be advised of the potential risk to a fetus
- Lactation: Small amounts of pregabalin have been detected in the milk of lactating women. Breastfeeding is not recommended
Precautions & Warnings
- Angioedema can occur and may be associated with life-threatening respiratory compromise
- Hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Respiratory depression may occur when used with concomitant CNS depressants
- Impairment of ability to drive or operate machinery
- Caution when coadministering with thiazolidinedione antidiabetic agents
Use in Special Populations
- Children and adolescents: Safety and effectiveness not established for various conditions
Overdose Effects
Signs and symptoms include reduced consciousness, depression/anxiety, confusional state, agitation, restlessness, seizures, and heart block. No specific antidote.
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
Keep in a cool & dry place (below 30°C), protected from light & moisture. Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
- Chemical Structure: Image available
Common Questions about Prelin 100 mg Capsule
- Anticonvulsant and first-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- To be taken till improvement in health conditions is observed
- To be taken in prescribed dosage after food
- Storage and disposal instructions
- Different effects for different diseases
- Duration of usage depends on the condition
- Not to be discontinued without consulting a doctor
- May be used with Diazepam
- Potential side effects and precautions